| Title |
The absorption of orally supplied β-alanine and its effect on muscle carnosine synthesis in human vastus lateralis
|
|---|---|
| Published in |
Amino Acids, March 2006
|
| DOI | 10.1007/s00726-006-0299-9 |
| Pubmed ID | |
| Authors |
R. C. Harris, M. J. Tallon, M. Dunnett, L. Boobis, J. Coakley, H. J. Kim, J. L. Fallowfield, C. A. Hill, C. Sale, J. A. Wise |
| Abstract |
Beta-alanine in blood-plasma when administered as A) histidine dipeptides (equivalent to 40 mg . kg(-1) bwt of beta-alanine) in chicken broth, or B) 10, C) 20 and D) 40 mg . kg(-1) bwt beta-alanine (CarnoSyn, NAI, USA), peaked at 428 +/- SE 66, 47 +/- 13, 374 +/- 68 and 833 +/- 43 microM. Concentrations regained baseline at 2 h. Carnosine was not detected in plasma with A) although traces of this and anserine were found in urine. Loss of beta-alanine in urine with B) to D) was <5%. Plasma taurine was increased by beta-alanine ingestion but this did not result in any increased loss via urine. Pharmacodynamics were further investigated with 3 x B) per day given for 15 d. Dietary supplementation with I) 3.2 and II) 6.4 g . d(-1) beta-alanine (as multiple doses of 400 or 800 mg) or III) L-carnosine (isomolar to II) for 4 w resulted in significant increases in muscle carnosine estimated at 42.1, 64.2 and 65.8%. |
X Demographics
The data shown below were collected from the profiles of 9 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 3 | 33% |
| United Kingdom | 3 | 33% |
| Unknown | 3 | 33% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Scientists | 5 | 56% |
| Practitioners (doctors, other healthcare professionals) | 3 | 33% |
| Members of the public | 1 | 11% |
Mendeley readers
The data shown below were compiled from readership statistics for 447 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 2 | <1% |
| Germany | 1 | <1% |
| Brazil | 1 | <1% |
| Switzerland | 1 | <1% |
| New Zealand | 1 | <1% |
| Poland | 1 | <1% |
| Unknown | 440 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 92 | 21% |
| Student > Bachelor | 77 | 17% |
| Student > Ph. D. Student | 41 | 9% |
| Researcher | 29 | 6% |
| Student > Postgraduate | 24 | 5% |
| Other | 69 | 15% |
| Unknown | 115 | 26% |
| Readers by discipline | Count | As % |
|---|---|---|
| Sports and Recreations | 118 | 26% |
| Agricultural and Biological Sciences | 59 | 13% |
| Medicine and Dentistry | 45 | 10% |
| Nursing and Health Professions | 30 | 7% |
| Biochemistry, Genetics and Molecular Biology | 17 | 4% |
| Other | 53 | 12% |
| Unknown | 125 | 28% |
Attention Score in Context
This research output has an Altmetric Attention Score of 55. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 February 2024.
All research outputs
#770,256
of 25,366,663 outputs
Outputs from Amino Acids
#33
of 1,626 outputs
Outputs of similar age
#1,075
of 81,690 outputs
Outputs of similar age from Amino Acids
#1
of 12 outputs
Altmetric has tracked 25,366,663 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 96th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,626 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.7. This one has done particularly well, scoring higher than 98% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 81,690 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 98% of its contemporaries.
We're also able to compare this research output to 12 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 99% of its contemporaries.