| Title |
Influence of β-alanine supplementation on skeletal muscle carnosine concentrations and high intensity cycling capacity
|
|---|---|
| Published in |
Amino Acids, July 2006
|
| DOI | 10.1007/s00726-006-0364-4 |
| Pubmed ID | |
| Authors |
C. A. Hill, R. C. Harris, H. J. Kim, B. D. Harris, C. Sale, L. H. Boobis, C. K. Kim, J. A. Wise |
| Abstract |
Muscle carnosine synthesis is limited by the availability of beta-alanine. Thirteen male subjects were supplemented with beta-alanine (CarnoSyn) for 4 wks, 8 of these for 10 wks. A biopsy of the vastus lateralis was obtained from 6 of the 8 at 0, 4 and 10 wks. Subjects undertook a cycle capacity test to determine total work done (TWD) at 110% (CCT(110%)) of their maximum power (Wmax). Twelve matched subjects received a placebo. Eleven of these completed the CCT(110%) at 0 and 4 wks, and 8, 10 wks. Muscle biopsies were obtained from 5 of the 8 and one additional subject. Muscle carnosine was significantly increased by +58.8% and +80.1% after 4 and 10 wks beta-alanine supplementation. Carnosine, initially 1.71 times higher in type IIa fibres, increased equally in both type I and IIa fibres. No increase was seen in control subjects. Taurine was unchanged by 10 wks of supplementation. 4 wks beta-alanine supplementation resulted in a significant increase in TWD (+13.0%); with a further +3.2% increase at 10 wks. TWD was unchanged at 4 and 10 wks in the control subjects. The increase in TWD with supplementation followed the increase in muscle carnosine. |
X Demographics
The data shown below were collected from the profiles of 9 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 3 | 33% |
| United Kingdom | 3 | 33% |
| Canada | 2 | 22% |
| Unknown | 1 | 11% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 7 | 78% |
| Scientists | 2 | 22% |
Mendeley readers
The data shown below were compiled from readership statistics for 446 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Germany | 1 | <1% |
| Switzerland | 1 | <1% |
| Australia | 1 | <1% |
| Brazil | 1 | <1% |
| United Kingdom | 1 | <1% |
| Canada | 1 | <1% |
| Spain | 1 | <1% |
| Poland | 1 | <1% |
| Unknown | 438 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 94 | 21% |
| Student > Master | 88 | 20% |
| Student > Ph. D. Student | 37 | 8% |
| Student > Postgraduate | 32 | 7% |
| Researcher | 29 | 7% |
| Other | 64 | 14% |
| Unknown | 102 | 23% |
| Readers by discipline | Count | As % |
|---|---|---|
| Sports and Recreations | 131 | 29% |
| Agricultural and Biological Sciences | 56 | 13% |
| Medicine and Dentistry | 43 | 10% |
| Nursing and Health Professions | 28 | 6% |
| Biochemistry, Genetics and Molecular Biology | 17 | 4% |
| Other | 48 | 11% |
| Unknown | 123 | 28% |
Attention Score in Context
This research output has an Altmetric Attention Score of 70. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 February 2024.
All research outputs
#581,972
of 24,588,574 outputs
Outputs from Amino Acids
#24
of 1,589 outputs
Outputs of similar age
#723
of 69,248 outputs
Outputs of similar age from Amino Acids
#2
of 9 outputs
Altmetric has tracked 24,588,574 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 97th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,589 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.1. This one has done particularly well, scoring higher than 98% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 69,248 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 98% of its contemporaries.
We're also able to compare this research output to 9 others from the same source and published within six weeks on either side of this one. This one has scored higher than 7 of them.