Title |
BAK, BAX, and NBK/BIK Proapoptotic Gene Alterations in Iranian Patients with Ataxia Telangiectasia
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Published in |
Journal of Clinical Immunology, November 2009
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DOI | 10.1007/s10875-009-9340-6 |
Pubmed ID | |
Authors |
Anna Isaian, Natalia V. Bogdanova, Masoud Houshmand, Masoud Movahadi, Asghar Agamohammadi, Nima Rezaei, Lida Atarod, Mahnaz Sadeghi-Shabestari, Seyed Hasan Tonekaboni, Zahra Chavoshzadeh, Seyed Mohammad Seyed Hassani, Reza Mirfakhrai, Taher Cheraghi, Najmoddin Kalantari, Mitra Ataei, Thilo Dork-Bousset, Mohammad Hossein Sanati |
Abstract |
Ataxia telangiectasia (AT) is an autosomal recessive multisystem disorder characterized by variable immunodeficiency, progressive neurodegeneration, occulocutaneous telangiectasia, and an increased susceptibility to malignancies. This study was designed to study the role of proapoptotic BAK, BAX, and NBK/BIK genes in a group of patients with AT to elucidate the possible role of these genes in progression of malignancies in this disease. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Israel | 1 | 5% |
Unknown | 18 | 95% |
Demographic breakdown
Readers by professional status | Count | As % |
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Professor > Associate Professor | 3 | 16% |
Researcher | 3 | 16% |
Professor | 3 | 16% |
Student > Bachelor | 2 | 11% |
Other | 1 | 5% |
Other | 2 | 11% |
Unknown | 5 | 26% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 6 | 32% |
Agricultural and Biological Sciences | 3 | 16% |
Biochemistry, Genetics and Molecular Biology | 2 | 11% |
Immunology and Microbiology | 1 | 5% |
Neuroscience | 1 | 5% |
Other | 0 | 0% |
Unknown | 6 | 32% |