Title |
Diagnosing metabolic acidosis in the critically ill: bridging the anion gap, Stewart, and base excess methods
|
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Published in |
Canadian Journal of Anesthesia/Journal canadien d'anesthésie, February 2009
|
DOI | 10.1007/s12630-008-9037-y |
Pubmed ID | |
Authors |
Christina Fidkowski, James Helstrom |
Abstract |
Metabolic acid-base disorders are common in critically ill patients. Clinicians may have difficulty recognizing their presence when multiple metabolic acid-base derangements are present in a single patient. Clinicians should be able to identify the components of complex metabolic acid-base disorders since metabolic acidoses due to unmeasured anions are associated with increased mortality in critically ill patients. This review presents the derivation of three commonly used methods of acid-base analysis, which include the anion gap, Stewart physiochemical, and modified base excess. Clinical examples are also provided to demonstrate the subtleties of the different methods and to demonstrate their application to real patient data. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Indonesia | 2 | 2% |
Italy | 1 | <1% |
South Africa | 1 | <1% |
Canada | 1 | <1% |
Japan | 1 | <1% |
United States | 1 | <1% |
Unknown | 105 | 94% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Other | 23 | 21% |
Researcher | 17 | 15% |
Student > Postgraduate | 17 | 15% |
Student > Bachelor | 12 | 11% |
Student > Master | 10 | 9% |
Other | 24 | 21% |
Unknown | 9 | 8% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 86 | 77% |
Nursing and Health Professions | 3 | 3% |
Agricultural and Biological Sciences | 3 | 3% |
Biochemistry, Genetics and Molecular Biology | 2 | 2% |
Immunology and Microbiology | 2 | 2% |
Other | 7 | 6% |
Unknown | 9 | 8% |