Title |
Influence of lumbar intervertebral disc degeneration on the outcome of total lumbar disc replacement: a prospective clinical, histological, X-ray and MRI investigation
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Published in |
European Spine Journal, May 2012
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DOI | 10.1007/s00586-012-2342-8 |
Pubmed ID | |
Authors |
Christoph J. Siepe, Franziska Heider, Elisabeth Haas, Wolfgang Hitzl, Ulrike Szeimies, Axel Stäbler, Christoph Weiler, Andreas G. Nerlich, Michael H. Mayer |
Abstract |
The role of fusion of lumbar motion segments for the treatment of axial low back pain (LBP) from lumbar degenerative disc disease (DDD) without any true deformities or instabilities remains controversially debated. In an attempt to avoid previously published and fusion-related negative side effects, motion preserving technologies such as total lumbar disc replacement (TDR) have been introduced. The adequate extent of preoperative DDD for TDR remains unknown, the number of previously published studies is scarce and the limited data available reveal contradictory results. The goal of this current analysis was to perform a prospective histological, X-ray and MRI investigation of the index-segment's degree of DDD and to correlate these data with each patient's pre- and postoperative clinical outcome parameters from an ongoing prospective clinical trial with ProDisc II (Synthes, Paoli, U.S.A.). |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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United Kingdom | 1 | 1% |
United States | 1 | 1% |
Unknown | 89 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 13 | 14% |
Student > Master | 13 | 14% |
Other | 10 | 11% |
Student > Ph. D. Student | 10 | 11% |
Student > Bachelor | 6 | 7% |
Other | 18 | 20% |
Unknown | 21 | 23% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 34 | 37% |
Nursing and Health Professions | 6 | 7% |
Engineering | 6 | 7% |
Veterinary Science and Veterinary Medicine | 5 | 5% |
Business, Management and Accounting | 3 | 3% |
Other | 14 | 15% |
Unknown | 23 | 25% |