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Improvements in Cystic Fibrosis Lung Disease and Airway Inflammation Associated with Etanercept Therapy for Rheumatoid Arthritis: A Case Report

Overview of attention for article published in Lung, June 2012
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Title
Improvements in Cystic Fibrosis Lung Disease and Airway Inflammation Associated with Etanercept Therapy for Rheumatoid Arthritis: A Case Report
Published in
Lung, June 2012
DOI 10.1007/s00408-012-9393-9
Pubmed ID
Authors

S. Visser, M. Martin, D. J. Serisier

Abstract

Cystic fibrosis (CF) lung pathology is characterized by excessive neutrophilic inflammation and high tumor necrosis factor-alpha (TNF-α) levels. A cornerstone of CF management is reduction of the inflammatory burden in the lung. We present the case of a 19-year-old CF patient who demonstrated significant clinical improvement in her lung disease associated with a reduction in sputum percent neutrophils, following commencement of etanercept (TNF-α antagonist) for rheumatoid arthritis. She has not had any infectious complications or other significant adverse effects during 2 years of treatment. It may be time to reconsider TNF-α antagonists as potential anti-inflammatory agents for CF lung disease.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 29 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 29 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 7 24%
Student > Doctoral Student 5 17%
Student > Master 4 14%
Student > Postgraduate 2 7%
Professor > Associate Professor 2 7%
Other 5 17%
Unknown 4 14%
Readers by discipline Count As %
Medicine and Dentistry 17 59%
Pharmacology, Toxicology and Pharmaceutical Science 3 10%
Biochemistry, Genetics and Molecular Biology 2 7%
Psychology 1 3%
Agricultural and Biological Sciences 1 3%
Other 0 0%
Unknown 5 17%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 February 2013.
All research outputs
#17,659,617
of 22,668,244 outputs
Outputs from Lung
#624
of 883 outputs
Outputs of similar age
#123,986
of 166,741 outputs
Outputs of similar age from Lung
#5
of 8 outputs
Altmetric has tracked 22,668,244 research outputs across all sources so far. This one is in the 19th percentile – i.e., 19% of other outputs scored the same or lower than it.
So far Altmetric has tracked 883 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.2. This one is in the 25th percentile – i.e., 25% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 166,741 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 22nd percentile – i.e., 22% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 8 others from the same source and published within six weeks on either side of this one. This one has scored higher than 3 of them.