↓ Skip to main content

A Historical Overview of Natural Products in Drug Discovery

Overview of attention for article published in Metabolites, April 2012
Altmetric Badge

About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • Among the highest-scoring outputs from this source (#24 of 3,226)
  • High Attention Score compared to outputs of the same age (98th percentile)

Mentioned by

news
8 news outlets
blogs
3 blogs
policy
2 policy sources
twitter
24 X users
patent
3 patents
facebook
1 Facebook page
wikipedia
7 Wikipedia pages
video
1 YouTube creator

Citations

dimensions_citation
1274 Dimensions

Readers on

mendeley
3440 Mendeley
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
A Historical Overview of Natural Products in Drug Discovery
Published in
Metabolites, April 2012
DOI 10.3390/metabo2020303
Pubmed ID
Authors

Daniel A. Dias, Sylvia Urban, Ute Roessner

Abstract

Historically, natural products have been used since ancient times and in folklore for the treatment of many diseases and illnesses. Classical natural product chemistry methodologies enabled a vast array of bioactive secondary metabolites from terrestrial and marine sources to be discovered. Many of these natural products have gone on to become current drug candidates. This brief review aims to highlight historically significant bioactive marine and terrestrial natural products, their use in folklore and dereplication techniques to rapidly facilitate their discovery. Furthermore a discussion of how natural product chemistry has resulted in the identification of many drug candidates; the application of advanced hyphenated spectroscopic techniques to aid in their discovery, the future of natural product chemistry and finally adopting metabolomic profiling and dereplication approaches for the comprehensive study of natural product extracts will be discussed.

X Demographics

X Demographics

The data shown below were collected from the profiles of 24 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 3,440 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Brazil 6 <1%
Mexico 5 <1%
India 5 <1%
Germany 4 <1%
Nigeria 3 <1%
Malaysia 3 <1%
United Kingdom 3 <1%
Pakistan 2 <1%
Chile 2 <1%
Other 12 <1%
Unknown 3395 99%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 596 17%
Student > Master 543 16%
Student > Bachelor 490 14%
Researcher 268 8%
Student > Doctoral Student 154 4%
Other 468 14%
Unknown 921 27%
Readers by discipline Count As %
Chemistry 819 24%
Agricultural and Biological Sciences 439 13%
Biochemistry, Genetics and Molecular Biology 416 12%
Pharmacology, Toxicology and Pharmaceutical Science 290 8%
Medicine and Dentistry 86 3%
Other 344 10%
Unknown 1046 30%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 110. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 02 April 2024.
All research outputs
#390,203
of 26,017,215 outputs
Outputs from Metabolites
#24
of 3,226 outputs
Outputs of similar age
#1,581
of 163,782 outputs
Outputs of similar age from Metabolites
#1
of 1 outputs
Altmetric has tracked 26,017,215 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 98th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,226 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.8. This one has done particularly well, scoring higher than 99% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 163,782 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 98% of its contemporaries.
We're also able to compare this research output to 1 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them