Title |
The life cycle of Trypanosoma (Nannomonas) congolense in the tsetse fly
|
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Published in |
Parasites & Vectors, June 2012
|
DOI | 10.1186/1756-3305-5-109 |
Pubmed ID | |
Authors |
Lori Peacock, Simon Cook, Vanessa Ferris, Mick Bailey, Wendy Gibson |
Abstract |
The tsetse-transmitted African trypanosomes cause diseases of importance to the health of both humans and livestock. The life cycles of these trypanosomes in the fly were described in the last century, but comparatively few details are available for Trypanosoma (Nannomonas) congolense, despite the fact that it is probably the most prevalent and widespread pathogenic species for livestock in tropical Africa. When the fly takes up bloodstream form trypanosomes, the initial establishment of midgut infection and invasion of the proventriculus is much the same in T. congolense and T. brucei. However, the developmental pathways subsequently diverge, with production of infective metacyclics in the proboscis for T. congolense and in the salivary glands for T. brucei. Whereas events during migration from the proventriculus are understood for T. brucei, knowledge of the corresponding developmental pathway in T. congolense is rudimentary. The recent publication of the genome sequence makes it timely to re-investigate the life cycle of T. congolense. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Germany | 1 | <1% |
Tanzania, United Republic of | 1 | <1% |
Uganda | 1 | <1% |
Brazil | 1 | <1% |
India | 1 | <1% |
United Kingdom | 1 | <1% |
United States | 1 | <1% |
Unknown | 178 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 38 | 21% |
Student > Bachelor | 26 | 14% |
Researcher | 25 | 14% |
Student > Master | 25 | 14% |
Student > Doctoral Student | 8 | 4% |
Other | 22 | 12% |
Unknown | 41 | 22% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 62 | 34% |
Biochemistry, Genetics and Molecular Biology | 37 | 20% |
Medicine and Dentistry | 10 | 5% |
Veterinary Science and Veterinary Medicine | 9 | 5% |
Immunology and Microbiology | 7 | 4% |
Other | 15 | 8% |
Unknown | 45 | 24% |