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Circulating miR‐34a levels are reduced in colorectal cancer

Overview of attention for article published in Seminars in Surgical Oncology, May 2012
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Title
Circulating miR‐34a levels are reduced in colorectal cancer
Published in
Seminars in Surgical Oncology, May 2012
DOI 10.1002/jso.23174
Pubmed ID
Authors

M. Nugent, N. Miller, M.J. Kerin

Abstract

MicroRNAs (miRNAs) are small, non-coding RNA segments that regulate gene expression via post-transcriptional inhibition and have roles in cell differentiation, proliferation, and apoptosis. Expression differs between tumor and normal tissue in several malignancies. Most work has focused on tissue and cell expression with few reports of circulating miRNAs in colorectal cancer. Available biomarkers for colorectal cancer have limited sensitivity and specificity, thus there is a need for new markers.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 66 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 3%
Denmark 1 2%
Germany 1 2%
Egypt 1 2%
Unknown 61 92%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 17 26%
Student > Master 12 18%
Researcher 11 17%
Student > Bachelor 9 14%
Other 3 5%
Other 8 12%
Unknown 6 9%
Readers by discipline Count As %
Agricultural and Biological Sciences 24 36%
Medicine and Dentistry 15 23%
Biochemistry, Genetics and Molecular Biology 10 15%
Pharmacology, Toxicology and Pharmaceutical Science 2 3%
Immunology and Microbiology 2 3%
Other 4 6%
Unknown 9 14%