Title |
Current evidence that exercise can increase the number of adult stem cells
|
---|---|
Published in |
Journal of Muscle Research and Cell Motility, June 2012
|
DOI | 10.1007/s10974-012-9302-0 |
Pubmed ID | |
Authors |
F. Macaluso, K. H. Myburgh |
Abstract |
The number of adult stem cells (ASCs) is very small, limiting the regenerative potential of tissues. One of the most studied ASCs in humans is the satellite cell (SC), which proliferates and increases pool size under exercise stress and muscle damage. This review examines the growth factor response to specific types of exercise to show the potential of exercise to stimulate not only SC self-renewal, but also other ASCs. We postulate that the same factors that stimulate a high proliferation of SCs in skeletal muscle after physical exercise should also stimulate the proliferation of ASCs in the tissue in which they reside, such as heart, bone, liver and etc. Regular exercise should be promoted, not only for disease prevention, but to maintain a high ASCs reserve and progenitor cell potential for rapid activation in response to future stressors and damage. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 2 | 40% |
Norway | 1 | 20% |
United States | 1 | 20% |
Sweden | 1 | 20% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 5 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 2 | 2% |
United Kingdom | 1 | <1% |
France | 1 | <1% |
Brazil | 1 | <1% |
Unknown | 114 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 22 | 18% |
Student > Ph. D. Student | 19 | 16% |
Researcher | 17 | 14% |
Student > Bachelor | 14 | 12% |
Student > Doctoral Student | 8 | 7% |
Other | 12 | 10% |
Unknown | 27 | 23% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 23 | 19% |
Medicine and Dentistry | 20 | 17% |
Biochemistry, Genetics and Molecular Biology | 14 | 12% |
Sports and Recreations | 10 | 8% |
Nursing and Health Professions | 8 | 7% |
Other | 14 | 12% |
Unknown | 30 | 25% |