Title |
The genetic epidemiology of idiopathic scoliosis
|
---|---|
Published in |
European Spine Journal, June 2012
|
DOI | 10.1007/s00586-012-2389-6 |
Pubmed ID | |
Authors |
Kristen Fay Gorman, Cédric Julien, Alain Moreau |
Abstract |
Idiopathic scoliosis is a complex developmental syndrome defined by an abnormal structural curvature of the spine. High treatment costs, chronic pain/discomfort, and the need for monitoring at-risk individuals contribute to the global healthcare burden of this musculoskeletal disease. Although many studies have endeavored to identify underlying genes, little progress has been made in understanding the etiopathogenesis. The objective of this comprehensive review was to summarize genetic associations/linkages with idiopathic scoliosis, as well as explore the strengths and weaknesses of each study, such that it may serve as a guide for the design and interpretation of future genetic studies in scoliosis. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Australia | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Scientists | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 2 | 1% |
United Kingdom | 1 | <1% |
Brazil | 1 | <1% |
Spain | 1 | <1% |
Poland | 1 | <1% |
Unknown | 139 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 25 | 17% |
Researcher | 18 | 12% |
Student > Ph. D. Student | 16 | 11% |
Student > Master | 9 | 6% |
Student > Postgraduate | 8 | 6% |
Other | 26 | 18% |
Unknown | 43 | 30% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 37 | 26% |
Biochemistry, Genetics and Molecular Biology | 22 | 15% |
Agricultural and Biological Sciences | 14 | 10% |
Nursing and Health Professions | 5 | 3% |
Social Sciences | 4 | 3% |
Other | 13 | 9% |
Unknown | 50 | 34% |