Title |
HDX Workbench: Software for the Analysis of H/D Exchange MS Data
|
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Published in |
Journal of the American Society for Mass Spectrometry, June 2012
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DOI | 10.1007/s13361-012-0419-6 |
Pubmed ID | |
Authors |
Bruce D. Pascal, Scooter Willis, Janelle L. Lauer, Rachelle R. Landgraf, Graham M. West, David Marciano, Scott Novick, Devrishi Goswami, Michael J. Chalmers, Patrick R. Griffin |
Abstract |
Hydrogen/deuterium exchange mass spectrometry (HDX-MS) is an established method for the interrogation of protein conformation and dynamics. While the data analysis challenge of HDX-MS has been addressed by a number of software packages, new computational tools are needed to keep pace with the improved methods and throughput of this technique. To address these needs, we report an integrated desktop program titled HDX Workbench, which facilitates automation, management, visualization, and statistical cross-comparison of large HDX data sets. Using the software, validated data analysis can be achieved at the rate of generation. The application is available at the project home page http://hdx.florida.scripps.edu . |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Scientists | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 1 | <1% |
Korea, Republic of | 1 | <1% |
United States | 1 | <1% |
Brazil | 1 | <1% |
Unknown | 131 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 40 | 30% |
Researcher | 27 | 20% |
Student > Master | 13 | 10% |
Student > Bachelor | 8 | 6% |
Student > Postgraduate | 7 | 5% |
Other | 21 | 16% |
Unknown | 19 | 14% |
Readers by discipline | Count | As % |
---|---|---|
Biochemistry, Genetics and Molecular Biology | 37 | 27% |
Chemistry | 32 | 24% |
Agricultural and Biological Sciences | 26 | 19% |
Engineering | 4 | 3% |
Pharmacology, Toxicology and Pharmaceutical Science | 2 | 1% |
Other | 10 | 7% |
Unknown | 24 | 18% |