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The methodology of the GUSTO cohort study: a novel approach in studying pediatric allergy

Overview of attention for article published in Asia Pacific Allergy, April 2012
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  • Good Attention Score compared to outputs of the same age (66th percentile)

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Title
The methodology of the GUSTO cohort study: a novel approach in studying pediatric allergy
Published in
Asia Pacific Allergy, April 2012
DOI 10.5415/apallergy.2012.2.2.144
Pubmed ID
Authors

Shu E Soh, Samuel Shang Ming Lee, Sarah Wenli Hoon, Mae Yun Tan, Anne Goh, Bee Wah Lee, Lynette Pei-Chi Shek, Oon Hoe Teoh, Kenneth Kwek, Seang Mei Saw, Keith Godfrey, Yap Seng Chong, Peter Gluckman, Hugo PS van Bever

Abstract

Growing Up in Singapore Towards healthy Outcomes (GUSTO) is Singapore's largest birth cohort study to date. The main aim of GUSTO is to evaluate the role of developmental factors in the early pathways to metabolic compromise. Detailed data is collected for a range of environmental exposures in the parents and offspring, and allergic disorders are among a number of outcomes assessed in infancy and childhood. Under the Allergy domain of GUSTO, this integrated study will describe the epidemiology of allergic manifestations and different phenotypes in the Asian context and help shed light on the association of metabolic disease to allergy. Epigenetic mechanisms and associations with other childhood disorders will also be explored. The aim of this report is to focus on methodology of GUSTO, and to suggest similar approaches (i.e., integrated cohort studies on pediatric allergy) worldwide. Recruitment commenced in 2009 with a cohort of 1,163 pregnant mothers in their first trimester. The mothers and children were followed throughout pregnancy and follow-up will continue until the child reaches 3 years of age. Preliminary results showed that 39.8% of the mothers had a personal history of having at least one allergic disease, which included asthma, eczema and allergic rhinitis. Further data collection and analyses are still ongoing. Allergy is a complex spectrum of disorders with numerous poorly-understood aspects. The ongoing GUSTO cohort study, with its longitudinal design and multi-disciplinary nature, may provide new insights into developmental influences on allergy. As a Singapore-based study, it will be the first integrated allergy cohort in Southeast Asia, of which recruitment started during pregnancy.

X Demographics

X Demographics

The data shown below were collected from the profiles of 7 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 32 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 32 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 7 22%
Researcher 7 22%
Student > Ph. D. Student 5 16%
Student > Master 3 9%
Student > Doctoral Student 1 3%
Other 3 9%
Unknown 6 19%
Readers by discipline Count As %
Medicine and Dentistry 7 22%
Psychology 5 16%
Agricultural and Biological Sciences 4 13%
Pharmacology, Toxicology and Pharmaceutical Science 2 6%
Social Sciences 2 6%
Other 4 13%
Unknown 8 25%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 June 2012.
All research outputs
#8,262,107
of 25,374,647 outputs
Outputs from Asia Pacific Allergy
#61
of 258 outputs
Outputs of similar age
#56,748
of 175,214 outputs
Outputs of similar age from Asia Pacific Allergy
#4
of 6 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. This one has received more attention than most of these and is in the 66th percentile.
So far Altmetric has tracked 258 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.4. This one has gotten more attention than average, scoring higher than 74% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 175,214 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 66% of its contemporaries.
We're also able to compare this research output to 6 others from the same source and published within six weeks on either side of this one. This one has scored higher than 2 of them.