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MERP1: a mammalian ependymin-related protein gene differentially expressed in hematopoietic cells

Overview of attention for article published in Gene, March 2002
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3 patents

Citations

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34 Dimensions

Readers on

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27 Mendeley
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Title
MERP1: a mammalian ependymin-related protein gene differentially expressed in hematopoietic cells
Published in
Gene, March 2002
DOI 10.1016/s0378-1119(02)00434-1
Pubmed ID
Authors

Claudia C. Gregorio-King, Janet L. McLeod, Fiona McL. Collier, Gregory R. Collier, Karyn A. Bolton, Gavin J. Van Der Meer, Jim Apostolopoulos, Mark A. Kirkland

Abstract

We have utilized differential display polymerase chain reaction to investigate the gene expression of hematopoietic progenitor cells from adult bone marrow and umbilical cord blood. A differentially expressed gene was identified in CD34+ hematopoietic progenitor cells, with low expression in CD34- cells. We have obtained the full coding sequence of this gene which we designated human mammalian ependymin-related protein 1 (MERP1). Expression of MERP1 was found in a variety of normal human tissues, and is 4- and 10-fold higher in adult bone marrow and umbilical cord blood CD34+ cells, respectively, compared to CD34- cells. Additionally, MERP1 expression in a hematopoietic stem cell enriched population was down-regulated with proliferation and differentiation. Conceptual translation of the MERP1 open reading frame reveals significant homology to two families of glycoprotein calcium-dependant cell adhesion molecules: ependymins and protocadherins.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 27 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
France 2 7%
Unknown 25 93%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 7 26%
Student > Ph. D. Student 6 22%
Researcher 4 15%
Professor 2 7%
Student > Doctoral Student 2 7%
Other 2 7%
Unknown 4 15%
Readers by discipline Count As %
Agricultural and Biological Sciences 12 44%
Biochemistry, Genetics and Molecular Biology 4 15%
Neuroscience 2 7%
Medicine and Dentistry 2 7%
Environmental Science 1 4%
Other 1 4%
Unknown 5 19%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 July 2014.
All research outputs
#8,534,528
of 25,373,627 outputs
Outputs from Gene
#3,257
of 10,913 outputs
Outputs of similar age
#17,285
of 49,733 outputs
Outputs of similar age from Gene
#21
of 56 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. This one is in the 43rd percentile – i.e., 43% of other outputs scored the same or lower than it.
So far Altmetric has tracked 10,913 research outputs from this source. They receive a mean Attention Score of 3.8. This one is in the 36th percentile – i.e., 36% of its peers scored the same or lower than it.
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We're also able to compare this research output to 56 others from the same source and published within six weeks on either side of this one. This one is in the 3rd percentile – i.e., 3% of its contemporaries scored the same or lower than it.