| Title |
Autism Spectrum Disorder, Developmental and Psychiatric Features in 16p11.2 Duplication
|
|---|---|
| Published in |
Journal of Autism and Developmental Disorders, May 2016
|
| DOI | 10.1007/s10803-016-2807-4 |
| Pubmed ID | |
| Authors |
LeeAnne Green Snyder, Debra D’Angelo, Qixuan Chen, Raphael Bernier, Robin P. Goin-Kochel, Arianne Stevens Wallace, Jennifer Gerdts, Stephen Kanne, Leandra Berry, Lisa Blaskey, Emily Kuschner, Timothy Roberts, Elliot Sherr, Christa L. Martin, David H. Ledbetter, John E. Spiro, Wendy K. Chung, Ellen Hanson, on behalf of the Simons VIP consortium |
| Abstract |
The 16p11.2 duplication (BP4-BP5) is associated with Autism Spectrum Disorder (ASD), although significant heterogeneity exists. Quantitative ASD, behavioral and neuropsychological measures and DSM-IV diagnoses in child and adult carriers were compared with familial non-carrier controls, and to published results from deletion carriers. The 16p11.2 duplication phenotype ranges widely from asymptomatic presentation to significant disability. The most common diagnoses were intellectual disability, motor delays and Attention Deficit Hyperactivity Disorder in children, and anxiety in adults. ASD occurred in nearly 20 % of child cases, but a majority of carriers did not show the unique social features of ASD. The 16p11.2 duplication phenotype is characterized by wider variability than the reciprocal deletion, likely reflecting contributions from additional risk factors. |
X Demographics
The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Canada | 1 | 33% |
| United Kingdom | 1 | 33% |
| Unknown | 1 | 33% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Scientists | 1 | 33% |
| Members of the public | 1 | 33% |
| Practitioners (doctors, other healthcare professionals) | 1 | 33% |
Mendeley readers
The data shown below were compiled from readership statistics for 146 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| France | 2 | 1% |
| United States | 1 | <1% |
| Unknown | 143 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 28 | 19% |
| Student > Ph. D. Student | 24 | 16% |
| Researcher | 17 | 12% |
| Student > Doctoral Student | 9 | 6% |
| Student > Bachelor | 7 | 5% |
| Other | 21 | 14% |
| Unknown | 40 | 27% |
| Readers by discipline | Count | As % |
|---|---|---|
| Psychology | 36 | 25% |
| Medicine and Dentistry | 20 | 14% |
| Neuroscience | 12 | 8% |
| Agricultural and Biological Sciences | 8 | 5% |
| Biochemistry, Genetics and Molecular Biology | 7 | 5% |
| Other | 15 | 10% |
| Unknown | 48 | 33% |
Attention Score in Context
This research output has an Altmetric Attention Score of 5. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 December 2018.
All research outputs
#6,682,800
of 23,867,274 outputs
Outputs from Journal of Autism and Developmental Disorders
#2,472
of 5,240 outputs
Outputs of similar age
#102,165
of 337,577 outputs
Outputs of similar age from Journal of Autism and Developmental Disorders
#24
of 55 outputs
Altmetric has tracked 23,867,274 research outputs across all sources so far. This one has received more attention than most of these and is in the 71st percentile.
So far Altmetric has tracked 5,240 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 13.2. This one has gotten more attention than average, scoring higher than 52% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 337,577 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 69% of its contemporaries.
We're also able to compare this research output to 55 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 56% of its contemporaries.