| Title |
Cerebral cortex: a target and source of insulin?
|
|---|---|
| Published in |
Diabetologia, May 2016
|
| DOI | 10.1007/s00125-016-3996-2 |
| Pubmed ID | |
| Authors |
Éva A. Csajbók, Gábor Tamás |
| Abstract |
Recent results suggest that insulin is synthesised by a subpopulation of neurons in the cerebral cortex and neural progenitor cells of the hippocampus. Supplementing the slow supply of insulin to the brain by pancreatic beta cells, the insulin locally released by neurons provides a rapid means of regulating local microcircuits, effectively modulating synaptic transmission and on-demand energy homeostasis of neural networks. Modulation of insulin production by brain neurons via glucagon-like peptide 1 (GLP-1) agonists might be useful in counteracting diabetes, obesity and neurodegenerative diseases. Replacement of lost pancreatic beta cells by autologous transplantation of insulin-producing neural progenitor cells could be a viable therapy for diabetes. |
X Demographics
The data shown below were collected from the profiles of 8 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Japan | 1 | 13% |
| Czechia | 1 | 13% |
| India | 1 | 13% |
| United States | 1 | 13% |
| Unknown | 4 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 7 | 88% |
| Practitioners (doctors, other healthcare professionals) | 1 | 13% |
Mendeley readers
The data shown below were compiled from readership statistics for 132 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Hungary | 1 | <1% |
| Unknown | 131 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 19 | 14% |
| Student > Ph. D. Student | 18 | 14% |
| Researcher | 12 | 9% |
| Other | 8 | 6% |
| Student > Master | 8 | 6% |
| Other | 16 | 12% |
| Unknown | 51 | 39% |
| Readers by discipline | Count | As % |
|---|---|---|
| Neuroscience | 22 | 17% |
| Biochemistry, Genetics and Molecular Biology | 18 | 14% |
| Medicine and Dentistry | 12 | 9% |
| Agricultural and Biological Sciences | 8 | 6% |
| Pharmacology, Toxicology and Pharmaceutical Science | 7 | 5% |
| Other | 12 | 9% |
| Unknown | 53 | 40% |
Attention Score in Context
This research output has an Altmetric Attention Score of 5. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 March 2023.
All research outputs
#6,542,424
of 23,597,497 outputs
Outputs from Diabetologia
#2,645
of 5,131 outputs
Outputs of similar age
#101,060
of 334,913 outputs
Outputs of similar age from Diabetologia
#47
of 95 outputs
Altmetric has tracked 23,597,497 research outputs across all sources so far. This one has received more attention than most of these and is in the 72nd percentile.
So far Altmetric has tracked 5,131 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 23.4. This one is in the 48th percentile – i.e., 48% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 334,913 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 69% of its contemporaries.
We're also able to compare this research output to 95 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 51% of its contemporaries.