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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Discrepancies between primary tumor and metastasis: A literature review on clinically established biomarkers
|
|---|---|
| Published in |
Critical Reviews in Oncology/Hematology, June 2012
|
| DOI | 10.1016/j.critrevonc.2012.05.002 |
| Pubmed ID | |
| Authors |
Stéphane Vignot, Benjamin Besse, Fabrice André, Jean-Philippe Spano, Jean-Charles Soria |
| Abstract |
The identification of predictive factors of response is critical for the development and appropriate use of anti-cancer agents. The evaluation of biomarkers is usually performed by analyzing the primary tumor tissues but this approach does not take into account potential discrepancies between primary tumor and secondary lesions. This review proposes to describe currently available data regarding differential expression of established biomarkers between primary tumor and matched metastasis. In light of recent data, the need of iterative biopsies in metastatic setting has been suggested but technical and methodological limits in such analyses should not be ignored and this strategy cannot be definitively validated. Complementary studies are still needed since the question of spatial and temporal variability of biomarkers in solid tumors is clearly a key issue in an era where personalized therapy is strongly advocated by clinicians, researchers and patients. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Canada | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 71 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 1% |
| United States | 1 | 1% |
| Netherlands | 1 | 1% |
| Unknown | 68 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 20 | 28% |
| Student > Ph. D. Student | 9 | 13% |
| Student > Master | 6 | 8% |
| Other | 5 | 7% |
| Student > Bachelor | 3 | 4% |
| Other | 13 | 18% |
| Unknown | 15 | 21% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 31 | 44% |
| Agricultural and Biological Sciences | 11 | 15% |
| Biochemistry, Genetics and Molecular Biology | 5 | 7% |
| Engineering | 3 | 4% |
| Social Sciences | 2 | 3% |
| Other | 4 | 6% |
| Unknown | 15 | 21% |
Attention Score in Context
This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 03 February 2022.
All research outputs
#7,363,939
of 25,394,764 outputs
Outputs from Critical Reviews in Oncology/Hematology
#639
of 1,947 outputs
Outputs of similar age
#49,725
of 178,054 outputs
Outputs of similar age from Critical Reviews in Oncology/Hematology
#5
of 9 outputs
Altmetric has tracked 25,394,764 research outputs across all sources so far. This one has received more attention than most of these and is in the 69th percentile.
So far Altmetric has tracked 1,947 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.9. This one has gotten more attention than average, scoring higher than 65% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 178,054 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 70% of its contemporaries.
We're also able to compare this research output to 9 others from the same source and published within six weeks on either side of this one. This one has scored higher than 4 of them.