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The Ecology of Antibiotic Use in the ICU: Homogeneous Prescribing of Cefepime but Not Tazocin Selects for Antibiotic Resistant Infection

Overview of attention for article published in PLOS ONE, June 2012
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Mentioned by

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3 X users
facebook
1 Facebook page

Citations

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23 Dimensions

Readers on

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71 Mendeley
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Title
The Ecology of Antibiotic Use in the ICU: Homogeneous Prescribing of Cefepime but Not Tazocin Selects for Antibiotic Resistant Infection
Published in
PLOS ONE, June 2012
DOI 10.1371/journal.pone.0038719
Pubmed ID
Authors

Andrew N. Ginn, Agnieszka M. Wiklendt, Heather F. Gidding, Narelle George, James S. O’Driscoll, Sally R. Partridge, Brian I. O’Toole, Rita A. Perri, Joan Faoagali, John E. Gallagher, Jeffrey Lipman, Jonathan R. Iredell

Abstract

Antibiotic homogeneity is thought to drive resistance but in vivo data are lacking. In this study, we determined the impact of antibiotic homogeneity per se, and of cefepime versus antipseudomonal penicillin/β-lactamase inhibitor combinations (APP-β), on the likelihood of infection or colonisation with antibiotic resistant bacteria and/or two commonly resistant nosocomial pathogens (methicillin-resistant Staphylococcus aureus and Pseudomonas aeruginosa). A secondary question was whether antibiotic cycling was associated with adverse outcomes including mortality, length of stay, and antibiotic resistance.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 71 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 1%
Mexico 1 1%
Unknown 69 97%

Demographic breakdown

Readers by professional status Count As %
Researcher 9 13%
Student > Master 8 11%
Student > Ph. D. Student 8 11%
Student > Bachelor 6 8%
Lecturer 5 7%
Other 14 20%
Unknown 21 30%
Readers by discipline Count As %
Medicine and Dentistry 21 30%
Pharmacology, Toxicology and Pharmaceutical Science 7 10%
Agricultural and Biological Sciences 5 7%
Nursing and Health Professions 3 4%
Biochemistry, Genetics and Molecular Biology 3 4%
Other 9 13%
Unknown 23 32%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 23 July 2015.
All research outputs
#13,867,609
of 22,669,724 outputs
Outputs from PLOS ONE
#111,699
of 193,515 outputs
Outputs of similar age
#94,831
of 164,520 outputs
Outputs of similar age from PLOS ONE
#2,187
of 3,955 outputs
Altmetric has tracked 22,669,724 research outputs across all sources so far. This one is in the 37th percentile – i.e., 37% of other outputs scored the same or lower than it.
So far Altmetric has tracked 193,515 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 15.0. This one is in the 40th percentile – i.e., 40% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 164,520 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 41st percentile – i.e., 41% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 3,955 others from the same source and published within six weeks on either side of this one. This one is in the 43rd percentile – i.e., 43% of its contemporaries scored the same or lower than it.