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The Q705K Polymorphism in NLRP3 Is a Gain-of-Function Alteration Leading to Excessive Interleukin-1β and IL-18 Production

Overview of attention for article published in PLOS ONE, April 2012
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Title
The Q705K Polymorphism in NLRP3 Is a Gain-of-Function Alteration Leading to Excessive Interleukin-1β and IL-18 Production
Published in
PLOS ONE, April 2012
DOI 10.1371/journal.pone.0034977
Pubmed ID
Authors

Deepti Verma, Eva Särndahl, Henrik Andersson, Per Eriksson, Mats Fredrikson, Jan-Ingvar Jönsson, Maria Lerm, Peter Söderkvist

Abstract

The Q705K polymorphism in NLRP3 has been implicated in several chronic inflammatory diseases. In this study we determine the functional role of this commonly occurring polymorphism using an in-vitro system.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 87 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Spain 1 1%
Canada 1 1%
Brazil 1 1%
Unknown 84 97%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 16 18%
Researcher 16 18%
Student > Bachelor 13 15%
Student > Master 13 15%
Student > Doctoral Student 6 7%
Other 11 13%
Unknown 12 14%
Readers by discipline Count As %
Agricultural and Biological Sciences 20 23%
Medicine and Dentistry 19 22%
Biochemistry, Genetics and Molecular Biology 11 13%
Immunology and Microbiology 8 9%
Nursing and Health Professions 4 5%
Other 6 7%
Unknown 19 22%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 09 January 2020.
All research outputs
#15,246,403
of 22,669,724 outputs
Outputs from PLOS ONE
#129,821
of 193,515 outputs
Outputs of similar age
#103,193
of 161,958 outputs
Outputs of similar age from PLOS ONE
#2,385
of 3,728 outputs
Altmetric has tracked 22,669,724 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 193,515 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 15.0. This one is in the 24th percentile – i.e., 24% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 161,958 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 25th percentile – i.e., 25% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 3,728 others from the same source and published within six weeks on either side of this one. This one is in the 26th percentile – i.e., 26% of its contemporaries scored the same or lower than it.