Title |
A Novel Approach to the Nutrigenetics and Nutrigenomics of Obesity and Weight Management
|
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Published in |
Current Oncology Reports, May 2016
|
DOI | 10.1007/s11912-016-0529-6 |
Pubmed ID | |
Authors |
Yael T. Joffe, Christine A. Houghton |
Abstract |
Nutrigenetics and nutrigenomics, as well as diet and exercise, play an important role in the development and treatment of obesity and its comorbidities. If an individual's susceptibility to becoming obese and their responsiveness to weight loss interventions are to be understood, then it needs to be addressed at a molecular and metabolic level, including genetic interaction. This review proposes a three-pillar approach to more fully comprehend the complexity of diet-gene interactions in obesity. Peroxisomal proliferating-activated receptor gamma (PPARG) and mitochondrial uncoupling protein-1 (UCP-1) are explored in detail. Illustrating how an understanding of nutritional biochemistry, nutrigenomics, and nutrigenetics may be the key to understanding differences observed in the obese phenotype that vary both within and across populations. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 33% |
Australia | 1 | 33% |
Unknown | 1 | 33% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Scientists | 2 | 67% |
Members of the public | 1 | 33% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 165 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 41 | 25% |
Student > Master | 26 | 16% |
Student > Postgraduate | 11 | 7% |
Student > Ph. D. Student | 10 | 6% |
Other | 8 | 5% |
Other | 25 | 15% |
Unknown | 44 | 27% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 30 | 18% |
Nursing and Health Professions | 25 | 15% |
Biochemistry, Genetics and Molecular Biology | 20 | 12% |
Agricultural and Biological Sciences | 17 | 10% |
Chemistry | 4 | 2% |
Other | 16 | 10% |
Unknown | 53 | 32% |