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New hypothesis on pontine–frontal eye field connectivity in Kleine–Levin syndrome

Overview of attention for article published in Journal of Sleep Research, May 2016
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Title
New hypothesis on pontine–frontal eye field connectivity in Kleine–Levin syndrome
Published in
Journal of Sleep Research, May 2016
DOI 10.1111/jsr.12428
Pubmed ID
Authors

Maria Engström, Anne‐Marie Landtblom, Thomas Karlsson

Abstract

Previous studies have indicated involvement of the thalamus and the pons in Kleine-Levin syndrome. In the present study, functional connectivity of the thalamus and the pons was investigated in asymptomatic patients with Kleine-Levin syndrome and healthy controls. Twelve patients and 14 healthy controls were investigated by functional magnetic resonance imaging during rest. Resting state images were analysed using seed regions of interest in the thalamus and the pons. The results showed significantly lower functional connectivity between the pons and the frontal eye field in persons with Kleine-Levin syndrome compared with healthy controls. There were no connectivity differences involving the thalamus. Based on these findings, a relation is proposed between the sleep disorder Kleine-Levin syndrome and cerebral control of eye movements, which in turn is related to visual attention and working memory. This hypothesis has to be tested in future studies of oculomotor control in Kleine-Levin syndrome.

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The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 28 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Belgium 1 4%
Unknown 27 96%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 5 18%
Student > Master 4 14%
Researcher 4 14%
Student > Doctoral Student 3 11%
Other 2 7%
Other 6 21%
Unknown 4 14%
Readers by discipline Count As %
Medicine and Dentistry 7 25%
Neuroscience 4 14%
Psychology 3 11%
Pharmacology, Toxicology and Pharmaceutical Science 2 7%
Nursing and Health Professions 2 7%
Other 4 14%
Unknown 6 21%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 May 2016.
All research outputs
#22,003,549
of 24,549,201 outputs
Outputs from Journal of Sleep Research
#1,792
of 1,939 outputs
Outputs of similar age
#300,520
of 344,522 outputs
Outputs of similar age from Journal of Sleep Research
#26
of 32 outputs
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