Title |
Incidence of urinary tract infections and antibiotic resistance in the outpatient setting: a cross-sectional study
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Published in |
Infection, May 2016
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DOI | 10.1007/s15010-016-0910-2 |
Pubmed ID | |
Authors |
Louise Rossignol, Sophie Vaux, Sylvie Maugat, Alexandre Blake, Roxane Barlier, Beate Heym, Yann Le Strat, Thierry Blanchon, Thomas Hanslik, Bruno Coignard |
Abstract |
In 2012-2013, a cross-sectional survey was conducted in women visiting a general practitioner for urinary tract infection (UTI), to estimate the annual incidence of UTIs due to antibiotic-resistant Escherichia coli (E. coli). A sampling design (stratification, stages and sampling weights) was taken into account in all analyses. Urine analyses were performed for each woman and centralised in one laboratory. Among 538 included women, urine culture confirmed UTI in 75.2 % of cases. E. coli represented 82.8 % of species. Among E. coli, resistance (I + R) was most common to amoxicillin [38 % (95 % confidence interval 31.1-44.5)] and to trimethoprim/sulfamethoxazole [18.1 % (12.0-24.1)]. Resistance to ciprofloxacin and cefotaxime was lower [1.9 % in both cases, (0.3-3.5)], as it was for nitrofurantoin [0.4 (0-1.0)] and fosfomycin (0). Extended-spectrum β-lactamase (ESBL) represented 1.6 % of E. coli (0.2-2.9). Annual incidence rate of confirmed UTI was estimated at 2400 per 100,000 women (1800-3000). Incidence rates of UTI due to fluoroquinolone-resistant and ESBL-producing E. coli were estimated at 102 per 100,000 women (75-129) and at 32 (24-41), respectively. ESBL had been found in a community population, and even though the rate was low, it represents a warning and confirms that surveillance should continue. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 3 | 43% |
Colombia | 1 | 14% |
Belgium | 1 | 14% |
Unknown | 2 | 29% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 4 | 57% |
Science communicators (journalists, bloggers, editors) | 1 | 14% |
Scientists | 1 | 14% |
Practitioners (doctors, other healthcare professionals) | 1 | 14% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Russia | 1 | <1% |
Unknown | 128 | 99% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 24 | 19% |
Other | 13 | 10% |
Researcher | 11 | 9% |
Student > Ph. D. Student | 11 | 9% |
Student > Bachelor | 11 | 9% |
Other | 26 | 20% |
Unknown | 33 | 26% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 32 | 25% |
Immunology and Microbiology | 13 | 10% |
Agricultural and Biological Sciences | 9 | 7% |
Biochemistry, Genetics and Molecular Biology | 6 | 5% |
Pharmacology, Toxicology and Pharmaceutical Science | 6 | 5% |
Other | 20 | 16% |
Unknown | 43 | 33% |