| Title |
Family history of myocardial infarction, stroke and diabetes and cardiometabolic markers in children
|
|---|---|
| Published in |
Diabetologia, May 2016
|
| DOI | 10.1007/s00125-016-3988-2 |
| Pubmed ID | |
| Authors |
Nina E. Berentzen, Alet H. Wijga, Lenie van Rossem, Gerard H. Koppelman, Bo van Nieuwenhuizen, Ulrike Gehring, Annemieke M. W. Spijkerman, Henriëtte A. Smit |
| Abstract |
Despite the overlap in occurrence of cardiovascular disease (CVD) and type 2 diabetes and their risk factors, family history of these diseases has not yet been investigated simultaneously in relation to cardiometabolic markers in offspring. We examined how a family history of CVD and/or diabetes relates to cardiometabolic markers in offspring, and to what extent these diseases independently contribute to cardiometabolic markers. We used data from 1,374 12-year-old children and their parents participating in a birth cohort study in the Netherlands. Family history of CVD (myocardial infarction [MI] and stroke) and diabetes were reported by the parents. Children were classified as 'no', 'moderate' or 'strong' family history, based on early/late onset of disease in parents and grandparents. Cardiometabolic markers were measured at 12 years of age: waist circumference, cholesterol, blood pressure and HbA1c. Compared with those with no family history, children with a strong family history of MI and/or stroke and/or diabetes (29% of the study population) had 0.13 mmol/l higher total cholesterol (TC) (95% CI 0.03, 0.23) and 0.18 higher TC/HDL-cholesterol (HDLC) ratio (95% CI 0.04, 0.32). A strong family history of MI or diabetes was independently associated with unfavourable cardiometabolic markers specific to those diseases. These associations remained after adjusting for BMI. Children with a moderate family history had no unfavourable cardiometabolic markers. One-third of the children had a strong family history of CVD and/or diabetes. These children had higher TC levels and TC/HDLC ratios than children with no family history. A strong family history of MI or diabetes was independently associated with unfavourable cardiometabolic markers specific to those diseases. |
X Demographics
The data shown below were collected from the profiles of 20 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 3 | 15% |
| Canada | 2 | 10% |
| Greece | 1 | 5% |
| Malaysia | 1 | 5% |
| Mexico | 1 | 5% |
| Finland | 1 | 5% |
| Brazil | 1 | 5% |
| India | 1 | 5% |
| Spain | 1 | 5% |
| Other | 1 | 5% |
| Unknown | 7 | 35% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 11 | 55% |
| Scientists | 6 | 30% |
| Practitioners (doctors, other healthcare professionals) | 2 | 10% |
| Science communicators (journalists, bloggers, editors) | 1 | 5% |
Mendeley readers
The data shown below were compiled from readership statistics for 44 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 44 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 6 | 14% |
| Researcher | 6 | 14% |
| Student > Doctoral Student | 5 | 11% |
| Student > Bachelor | 4 | 9% |
| Student > Ph. D. Student | 3 | 7% |
| Other | 7 | 16% |
| Unknown | 13 | 30% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 17 | 39% |
| Biochemistry, Genetics and Molecular Biology | 3 | 7% |
| Sports and Recreations | 3 | 7% |
| Psychology | 2 | 5% |
| Nursing and Health Professions | 1 | 2% |
| Other | 3 | 7% |
| Unknown | 15 | 34% |
Attention Score in Context
This research output has an Altmetric Attention Score of 142. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 June 2019.
All research outputs
#267,765
of 24,041,016 outputs
Outputs from Diabetologia
#158
of 5,207 outputs
Outputs of similar age
#5,531
of 344,178 outputs
Outputs of similar age from Diabetologia
#5
of 87 outputs
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So far Altmetric has tracked 5,207 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 23.9. This one has done particularly well, scoring higher than 96% of its peers.
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We're also able to compare this research output to 87 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 95% of its contemporaries.