You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output.
Click here to find out more.
X Demographics
Mendeley readers
Attention Score in Context
| Title |
Control of Virulence by Small RNAs in Streptococcus pneumoniae
|
|---|---|
| Published in |
PLoS Pathogens, July 2012
|
| DOI | 10.1371/journal.ppat.1002788 |
| Pubmed ID | |
| Authors |
Beth Mann, Tim van Opijnen, Jianmin Wang, Caroline Obert, Yong-Dong Wang, Robert Carter, Daniel J. McGoldrick, Granger Ridout, Andrew Camilli, Elaine I. Tuomanen, Jason W. Rosch |
| Abstract |
Small noncoding RNAs (sRNAs) play important roles in gene regulation in both prokaryotes and eukaryotes. Thus far, no sRNA has been assigned a definitive role in virulence in the major human pathogen Streptococcus pneumoniae. Based on the potential coding capacity of intergenic regions, we hypothesized that the pneumococcus produces many sRNAs and that they would play an important role in pathogenesis. We describe the application of whole-genome transcriptional sequencing to systematically identify the sRNAs of Streptococcus pneumoniae. Using this approach, we have identified 89 putative sRNAs, 56 of which are newly identified. Furthermore, using targeted genetic approaches and Tn-seq transposon screening, we demonstrate that many of the identified sRNAs have important global and niche-specific roles in virulence. These data constitute the most comprehensive analysis of pneumococcal sRNAs and provide the first evidence of the extensive roles of sRNAs in pneumococcal pathogenesis. |
X Demographics
The data shown below were collected from the profiles of 14 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 3 | 21% |
| United Kingdom | 2 | 14% |
| New Zealand | 1 | 7% |
| France | 1 | 7% |
| Unknown | 7 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 10 | 71% |
| Scientists | 3 | 21% |
| Science communicators (journalists, bloggers, editors) | 1 | 7% |
Mendeley readers
The data shown below were compiled from readership statistics for 204 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 4 | 2% |
| United Kingdom | 2 | <1% |
| Germany | 1 | <1% |
| France | 1 | <1% |
| New Zealand | 1 | <1% |
| Netherlands | 1 | <1% |
| Belgium | 1 | <1% |
| Mexico | 1 | <1% |
| Spain | 1 | <1% |
| Other | 1 | <1% |
| Unknown | 190 | 93% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 66 | 32% |
| Researcher | 48 | 24% |
| Student > Bachelor | 18 | 9% |
| Student > Postgraduate | 12 | 6% |
| Student > Master | 12 | 6% |
| Other | 31 | 15% |
| Unknown | 17 | 8% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 108 | 53% |
| Biochemistry, Genetics and Molecular Biology | 37 | 18% |
| Immunology and Microbiology | 18 | 9% |
| Medicine and Dentistry | 6 | 3% |
| Engineering | 4 | 2% |
| Other | 7 | 3% |
| Unknown | 24 | 12% |
Attention Score in Context
This research output has an Altmetric Attention Score of 11. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 03 February 2023.
All research outputs
#3,202,565
of 25,374,917 outputs
Outputs from PLoS Pathogens
#2,956
of 9,468 outputs
Outputs of similar age
#20,532
of 177,928 outputs
Outputs of similar age from PLoS Pathogens
#32
of 137 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. Compared to these this one has done well and is in the 87th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 9,468 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 20.4. This one has gotten more attention than average, scoring higher than 68% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 177,928 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 88% of its contemporaries.
We're also able to compare this research output to 137 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 76% of its contemporaries.