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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Harnessing the immune system in acute myeloid leukaemia
|
|---|---|
| Published in |
Critical Reviews in Oncology/Hematology, May 2016
|
| DOI | 10.1016/j.critrevonc.2016.04.020 |
| Pubmed ID | |
| Authors |
Rebecca Austin, Mark J. Smyth, Steven W. Lane |
| Abstract |
Acute myeloid leukaemia (AML) is an aggressive blood cancer caused by the proliferation of immature myeloid cells. The genetic abnormalities underlying AML affect signal transduction pathways, transcription factors and epigenetic modifiers. In solid tumours, it is emerging that the genetic landscape of the tumour has a direct effect on the anti-tumour immune responses and response to immunotherapeutic treatment. However, there remains little information as to whether genetic abnormalities affect anti-leukemic immune responses. This review discusses current knowledge of AML antigens and immune responses to AML with a particular focus on the role of T cells and natural killer cells. Understanding immune responses to AML has implications for the development and use of immunotherapies to treat AML patients with distinct genetic abnormalities. |
X Demographics
The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| France | 1 | 25% |
| Unknown | 3 | 75% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 4 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 179 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Australia | 1 | <1% |
| Unknown | 178 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 30 | 17% |
| Student > Postgraduate | 29 | 16% |
| Researcher | 27 | 15% |
| Student > Bachelor | 18 | 10% |
| Student > Doctoral Student | 8 | 4% |
| Other | 22 | 12% |
| Unknown | 45 | 25% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 45 | 25% |
| Medicine and Dentistry | 32 | 18% |
| Agricultural and Biological Sciences | 27 | 15% |
| Immunology and Microbiology | 17 | 9% |
| Unspecified | 2 | 1% |
| Other | 9 | 5% |
| Unknown | 47 | 26% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 July 2016.
All research outputs
#16,045,990
of 25,368,786 outputs
Outputs from Critical Reviews in Oncology/Hematology
#1,300
of 1,946 outputs
Outputs of similar age
#180,362
of 323,893 outputs
Outputs of similar age from Critical Reviews in Oncology/Hematology
#20
of 30 outputs
Altmetric has tracked 25,368,786 research outputs across all sources so far. This one is in the 34th percentile – i.e., 34% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,946 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.8. This one is in the 30th percentile – i.e., 30% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 323,893 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 41st percentile – i.e., 41% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 30 others from the same source and published within six weeks on either side of this one. This one is in the 33rd percentile – i.e., 33% of its contemporaries scored the same or lower than it.