| Title |
Morbimortality in adult patients with septic arthritis: a three-year hospital-based study
|
|---|---|
| Published in |
BMC Infectious Diseases, June 2016
|
| DOI | 10.1186/s12879-016-1540-0 |
| Pubmed ID | |
| Authors |
Julien Ferrand, Youssef El Samad, Benoit Brunschweiler, Franck Grados, Nassima Dehamchia-Rehailia, Alice Séjourne, Jean-Luc Schmit, Antoine Gabrion, Patrice Fardellone, Julien Paccou |
| Abstract |
The objective of this ambispective study was to determine outcomes and associated factors for adult patients with confirmed septic arthritis (SA). All adult patients admitted to Amiens University Hospital between November 2010 and December 2013 with confirmed SA were included in the study. Patients with prosthetic joint infections were excluded. A statistical analysis was performed in order to identify risk factors associated with a poor outcome (including mortality directly attributable to SA). A total of 109 patients (mean ± SD age: 60.1 ± 20.1; 74 male/35 females) were diagnosed with SA during the study period. The most commonly involved sites were the small joints (n = 34, 31.2 %) and the knee (n = 25, 22.9 %). The most frequent concomitant conditions were cardiovascular disease (n = 45, 41.3 %) and rheumatic disease (n = 39, 35.8 %). One hundred patients (91.7 %) had a positive microbiological culture test, with Staphylococcus aureus as the most commonly detected pathogen (n = 59, 54.1 %). Mortality directly attributable to SA was relatively infrequent (n = 6, 5.6 %) and occurred soon after the onset of SA (median [range]: 24 days [1-42]). Major risk factors associated with death directly attributable to SA were older age (p = 0.023), high C-reactive protein levels (p = 0.002), diabetes mellitus (p = 0.028), rheumatoid arthritis and other inflammatory rheumatic diseases (p = 0.021), confusion on admission (p = 0.012), bacteraemia (p = 0.015), a low creatinine clearance rate (p = 0.009) and the presence of leg ulcers/eschars (p = 0.003). The median duration of follow-up (in patients who survived for more than 6 months) was 17 months [6-43]. The proportion of poor functional outcomes was high (31.8 %). Major risk factors associated with a poor functional outcome were older age (0.049), hip joint involvement (p = 0.003), the presence of leg ulcers/eschars (p = 0.012), longer time to presentation (0.034) and a low creatinine clearance rate (p = 0.013). In a university hospital setting, SA is still associated with high morbidity and mortality rates. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Venezuela, Bolivarian Republic of | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Scientists | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 128 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 128 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Postgraduate | 20 | 16% |
| Researcher | 15 | 12% |
| Student > Doctoral Student | 13 | 10% |
| Student > Bachelor | 11 | 9% |
| Student > Ph. D. Student | 11 | 9% |
| Other | 24 | 19% |
| Unknown | 34 | 27% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 48 | 38% |
| Nursing and Health Professions | 8 | 6% |
| Immunology and Microbiology | 7 | 5% |
| Biochemistry, Genetics and Molecular Biology | 3 | 2% |
| Pharmacology, Toxicology and Pharmaceutical Science | 3 | 2% |
| Other | 16 | 13% |
| Unknown | 43 | 34% |
Attention Score in Context
This research output has an Altmetric Attention Score of 10. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 June 2016.
All research outputs
#3,131,705
of 22,875,477 outputs
Outputs from BMC Infectious Diseases
#1,022
of 7,690 outputs
Outputs of similar age
#57,404
of 339,120 outputs
Outputs of similar age from BMC Infectious Diseases
#18
of 162 outputs
Altmetric has tracked 22,875,477 research outputs across all sources so far. Compared to these this one has done well and is in the 86th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 7,690 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.6. This one has done well, scoring higher than 86% of its peers.
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