| Title |
BRCA2 Variants and cardiovascular disease in a multi-ethnic study
|
|---|---|
| Published in |
BMC Medical Genomics, July 2012
|
| DOI | 10.1186/1471-2350-13-56 |
| Pubmed ID | |
| Authors |
Kevin Zbuk, Changchun Xie, Robin Young, Mahyar Heydarpour, Guillaume Pare, A Darlene Davis, Ruby Miller, Matthew B Lanktree, Danish Saleheen, John Danesh, Salim Yusuf, James C Engert, Robert A Hegele, Sonia S Anand |
| Abstract |
Germline mutations of BRCA1/2 are associated with hereditary breast and ovarian cancer. Recent data suggests excess mortality in mutation carriers beyond that conferred by neoplasia, and recent in vivo and in vitro studies suggest a modulatory role for BRCA proteins in endothelial and cardiomyocyte function. We therefore tested the association of BRCA2 variants with clinical cardiovascular disease (CVD). |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Germany | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Scientists | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 54 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Japan | 1 | 2% |
| United States | 1 | 2% |
| China | 1 | 2% |
| Unknown | 51 | 94% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 8 | 15% |
| Researcher | 7 | 13% |
| Student > Ph. D. Student | 7 | 13% |
| Student > Bachelor | 4 | 7% |
| Student > Doctoral Student | 3 | 6% |
| Other | 9 | 17% |
| Unknown | 16 | 30% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 13 | 24% |
| Biochemistry, Genetics and Molecular Biology | 7 | 13% |
| Agricultural and Biological Sciences | 7 | 13% |
| Nursing and Health Professions | 3 | 6% |
| Psychology | 3 | 6% |
| Other | 5 | 9% |
| Unknown | 16 | 30% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 July 2012.
All research outputs
#20,656,161
of 25,374,647 outputs
Outputs from BMC Medical Genomics
#1,682
of 2,444 outputs
Outputs of similar age
#139,216
of 178,038 outputs
Outputs of similar age from BMC Medical Genomics
#31
of 37 outputs
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We're also able to compare this research output to 37 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.