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Attention Score in Context
| Title |
Alterations in regional shape on ipsilateral and contralateral cortex contrast in children with unilateral cerebral palsy and are predictive of multiple outcomes
|
|---|---|
| Published in |
Human Brain Mapping, June 2016
|
| DOI | 10.1002/hbm.23262 |
| Pubmed ID | |
| Authors |
Alex M Pagnozzi, Nicholas Dowson, Simona Fiori, James Doecke, Andrew P Bradley, Roslyn N Boyd, Stephen Rose |
| Abstract |
Congenital brain lesions result in a wide range of cerebral tissue alterations observed in children with cerebral palsy (CP) that are associated with a range of functional impairments. The relationship between injury severity and functional outcomes, however, remains poorly understood. This research investigates the differences in cortical shape between children with congenital brain lesions and typically developing children (TDC) and investigates the correlations between cortical shape and functional outcome in a large cohort of patients diagnosed with unilateral CP. Using 139 structural magnetic resonance images, including 95 patients with clinically diagnosed CP and 44 TDC, cortical segmentations were obtained using a modified expectation maximization algorithm. Three shape characteristics (cortical thickness, curvature, and sulcal depth) were computed within a number of cortical regions. Significant differences in these shape measures compared to the TDC were observed on both the injured hemisphere of children with CP (P < 0.004), as well as on the apparently uninjured hemisphere, illustrating potential compensatory mechanisms in these children. Furthermore, these shape measures were significantly correlated with several functional outcomes, including motor, cognition, vision, and communication (P < 0.012), with three out of these four models performing well on test set validation. This study highlights that cortical neuroplastic effects may be quantified using MR imaging, allowing morphological changes to be studied longitudinally, including any influence of treatment. Ultimately, such approaches could be used for the long term prediction of outcomes and the tailoring of treatment to individuals. Hum Brain Mapp, 2016. © 2016 Wiley Periodicals, Inc. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 66 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 66 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 14 | 21% |
| Student > Master | 9 | 14% |
| Student > Doctoral Student | 8 | 12% |
| Student > Bachelor | 5 | 8% |
| Researcher | 4 | 6% |
| Other | 9 | 14% |
| Unknown | 17 | 26% |
| Readers by discipline | Count | As % |
|---|---|---|
| Psychology | 11 | 17% |
| Medicine and Dentistry | 10 | 15% |
| Neuroscience | 9 | 14% |
| Nursing and Health Professions | 3 | 5% |
| Computer Science | 2 | 3% |
| Other | 8 | 12% |
| Unknown | 23 | 35% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 04 June 2016.
All research outputs
#22,012,573
of 24,561,012 outputs
Outputs from Human Brain Mapping
#3,962
of 4,312 outputs
Outputs of similar age
#301,662
of 345,555 outputs
Outputs of similar age from Human Brain Mapping
#68
of 76 outputs
Altmetric has tracked 24,561,012 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 4,312 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.1. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 345,555 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 76 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.