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CRISPR/Cas9: From Genome Engineering to Cancer Drug Discovery

Overview of attention for article published in Trends in Cancer, June 2016
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (94th percentile)
  • Good Attention Score compared to outputs of the same age and source (73rd percentile)

Mentioned by

blogs
1 blog
twitter
55 X users
facebook
3 Facebook pages

Citations

dimensions_citation
43 Dimensions

Readers on

mendeley
193 Mendeley
citeulike
1 CiteULike
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Title
CRISPR/Cas9: From Genome Engineering to Cancer Drug Discovery
Published in
Trends in Cancer, June 2016
DOI 10.1016/j.trecan.2016.05.001
Pubmed ID
Authors

Ji Luo

Abstract

Advances in translational research are often driven by new technologies. The advent of microarrays, next-generation sequencing, proteomics and RNA interference (RNAi) have led to breakthroughs in our understanding of the mechanisms of cancer and the discovery of new cancer drug targets. The discovery of the bacterial clustered regularly interspaced palindromic repeat (CRISPR) system and its subsequent adaptation as a tool for mammalian genome engineering has opened up new avenues for functional genomics studies. This review will focus on the utility of CRISPR in the context of cancer drug target discovery.

X Demographics

X Demographics

The data shown below were collected from the profiles of 55 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 193 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Iran, Islamic Republic of 1 <1%
Mexico 1 <1%
Spain 1 <1%
Switzerland 1 <1%
Unknown 189 98%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 37 19%
Student > Ph. D. Student 36 19%
Researcher 29 15%
Student > Master 21 11%
Other 12 6%
Other 29 15%
Unknown 29 15%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 71 37%
Agricultural and Biological Sciences 35 18%
Medicine and Dentistry 17 9%
Pharmacology, Toxicology and Pharmaceutical Science 7 4%
Immunology and Microbiology 6 3%
Other 22 11%
Unknown 35 18%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 36. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 January 2018.
All research outputs
#1,143,386
of 25,839,971 outputs
Outputs from Trends in Cancer
#110
of 852 outputs
Outputs of similar age
#20,756
of 354,954 outputs
Outputs of similar age from Trends in Cancer
#6
of 23 outputs
Altmetric has tracked 25,839,971 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 95th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 852 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 18.7. This one has done well, scoring higher than 87% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 354,954 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 94% of its contemporaries.
We're also able to compare this research output to 23 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 73% of its contemporaries.