Title |
Value and level of circulating endothelial progenitor cells, angiogenesis factors and mononuclear cell apoptosis in patients with chronic kidney disease
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Published in |
Clinical and Experimental Nephrology, July 2012
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DOI | 10.1007/s10157-012-0664-9 |
Pubmed ID | |
Authors |
Yen-Ta Chen, Ben-Chung Cheng, Sheung-Fat Ko, Chih-Hung Chen, Tzu-Hsien Tsai, Steve Leu, Hsueh-Wen Chang, Sheng-Ying Chung, Sarah Chua, Kuo-Ho Yeh, Yung-Lung Chen, Hon-Kan Yip |
Abstract |
Chronic renal failure on dialysis can reduce the number of circulating endothelial progenitor cells (EPCs), but this biomarker has not been fully investigated in patients with chronic kidney disease (CKD). A link between CKD and increased mononuclear cell apoptosis (MCA) in circulation has been reported but the effect of vascular endothelial growth factor (VEGF) and stromal cell-derived factor (SDF)-1α, two angiogenesis factors, on circulating EPC levels in CKD has not been clarified. This study examined the relationships between the numbers of circulating EPCs and the severity of CKD, degree of MCA and serum levels of VEGF and SDF-1α in CKD patients. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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India | 1 | 3% |
Italy | 1 | 3% |
Unknown | 34 | 94% |
Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 10 | 28% |
Student > Ph. D. Student | 5 | 14% |
Other | 3 | 8% |
Professor > Associate Professor | 3 | 8% |
Student > Doctoral Student | 2 | 6% |
Other | 9 | 25% |
Unknown | 4 | 11% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 20 | 56% |
Biochemistry, Genetics and Molecular Biology | 4 | 11% |
Agricultural and Biological Sciences | 2 | 6% |
Chemical Engineering | 1 | 3% |
Pharmacology, Toxicology and Pharmaceutical Science | 1 | 3% |
Other | 2 | 6% |
Unknown | 6 | 17% |