| Title |
Structure and functions of linker histones
|
|---|---|
| Published in |
Biochemistry, March 2016
|
| DOI | 10.1134/s0006297916030032 |
| Pubmed ID | |
| Authors |
A. V. Lyubitelev, D. V. Nikitin, A. K. Shaytan, V. M. Studitsky, M. P. Kirpichnikov |
| Abstract |
Linker histones such as variants H1, H5, and other similar proteins play an important role in regulation of chromatin structure and dynamics. However, interactions of linker histones with DNA and proteins, as well as specific functions of their different variants, are poorly studied. This is because they acquire tertiary structure only when interacting with a nucleosome, and because of limitations of currently available methods. However, deeper investigation of linker histones and their interactions with other proteins will address a number of important questions - from structure of compacted chromatin to regulation of early embryogenesis. In this review, structures of histone H1 variants and its interaction with chromatin DNA are considered. A possible functional significance of different H1 variants, a role of these proteins in maintaining interphase chromatin structure, and interactions of linker histones with other cellular proteins are also discussed. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| France | 1 | 50% |
| Unknown | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 46 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Vietnam | 1 | 2% |
| Unknown | 45 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 12 | 26% |
| Student > Ph. D. Student | 9 | 20% |
| Student > Master | 7 | 15% |
| Student > Bachelor | 5 | 11% |
| Other | 2 | 4% |
| Other | 3 | 7% |
| Unknown | 8 | 17% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 19 | 41% |
| Agricultural and Biological Sciences | 7 | 15% |
| Physics and Astronomy | 3 | 7% |
| Medicine and Dentistry | 2 | 4% |
| Chemistry | 2 | 4% |
| Other | 3 | 7% |
| Unknown | 10 | 22% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 June 2016.
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#20,656,161
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Outputs from Biochemistry
#20,693
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#234,907
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Outputs of similar age from Biochemistry
#96
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