Title |
A Peculiar Cause of Anaphylaxis: No More steak?
|
---|---|
Published in |
Journal of General Internal Medicine, July 2012
|
DOI | 10.1007/s11606-012-2144-z |
Pubmed ID | |
Authors |
Susan E. Wolver, Diane R. Sun, Scott P. Commins, Lawrence B. Schwartz |
Abstract |
In recent years, a newly recognized allergic disease has been uncovered, and seemingly idiopathic causes of anaphylaxis now have an explanation. Individuals bitten by the lone star tick may develop IgE antibodies to the carbohydrate galactose-α-1,3-galactose (alpha-gal). Upon exposure of sensitized subjects to mammalian meat containing alpha-gal on glycoproteins or glycolipids, delayed anaphylaxis may ensue, often three to six hours after ingestion.1 Many of these individuals have negative allergy skin prick tests to meat, further obscuring the diagnosis. With the recent development of IgE alpha-gal tests, the clinical diagnosis can be confirmed in the laboratory. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 5 | 42% |
Canada | 2 | 17% |
Netherlands | 1 | 8% |
Unknown | 4 | 33% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 6 | 50% |
Practitioners (doctors, other healthcare professionals) | 3 | 25% |
Scientists | 2 | 17% |
Science communicators (journalists, bloggers, editors) | 1 | 8% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Japan | 1 | 3% |
Unknown | 38 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 10 | 26% |
Researcher | 5 | 13% |
Student > Ph. D. Student | 5 | 13% |
Student > Postgraduate | 4 | 10% |
Student > Doctoral Student | 4 | 10% |
Other | 6 | 15% |
Unknown | 5 | 13% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 9 | 23% |
Agricultural and Biological Sciences | 8 | 21% |
Biochemistry, Genetics and Molecular Biology | 4 | 10% |
Nursing and Health Professions | 3 | 8% |
Immunology and Microbiology | 3 | 8% |
Other | 5 | 13% |
Unknown | 7 | 18% |