Title |
The role of androgen and androgen receptor in skin-related disorders
|
---|---|
Published in |
Archives of Dermatological Research, July 2012
|
DOI | 10.1007/s00403-012-1265-x |
Pubmed ID | |
Authors |
Jiann-Jyh Lai, Philip Chang, Kuo-Pao Lai, Lumin Chen, Chawnshang Chang |
Abstract |
Androgen and androgen receptor (AR) may play important roles in several skin-related diseases, such as androgenetic alopecia and acne vulgaris. Current treatments for these androgen/AR-involved diseases, which target the synthesis of androgens or prevent its binding to AR, can cause significant adverse side effects. Based on the recent studies using AR knockout mice, it has been suggested that AR and androgens play distinct roles in the skin pathogenesis, and AR seems to be a better target than androgens for the treatment of these skin diseases. Here, we review recent studies of androgen/AR roles in several skin-related disorders, including acne vulgaris, androgenetic alopecia and hirsutism, as well as cutaneous wound healing. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 1 | 50% |
Unknown | 1 | 50% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 2 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
India | 1 | <1% |
Unknown | 203 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 36 | 18% |
Student > Master | 23 | 11% |
Researcher | 22 | 11% |
Student > Ph. D. Student | 20 | 10% |
Student > Postgraduate | 16 | 8% |
Other | 37 | 18% |
Unknown | 50 | 25% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 77 | 38% |
Agricultural and Biological Sciences | 22 | 11% |
Biochemistry, Genetics and Molecular Biology | 16 | 8% |
Pharmacology, Toxicology and Pharmaceutical Science | 12 | 6% |
Nursing and Health Professions | 6 | 3% |
Other | 16 | 8% |
Unknown | 55 | 27% |