Title |
The utility of bispectral index monitoring for sedated patients treated with low-dose remifentanil
|
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Published in |
Journal of Clinical Monitoring and Computing, July 2012
|
DOI | 10.1007/s10877-012-9379-4 |
Pubmed ID | |
Authors |
Takao Kato, Toshiya Koitabashi, Takashi Ouchi, Ryohei Serita |
Abstract |
The aim of the present study was to determine the effect of low-dose remifentanil on the monitoring quality of the Bispectral index for mechanically ventilated patients. Twelve patients who underwent elective surgery and required mechanical ventilation post-operatively were enrolled in this study with written informed consent. Eligible patients were divided into two groups. Patients in the remifentanil group received low-dose remifentanil (0.05-0.125 μg/kg/min) and propofol (1-3 mg/kg/h). Patients in the control group received propofol (1-3 mg/kg/h). Levels of sedation were evaluated by both the Richmond Agitation Sedation Scale (RASS) and BIS monitor (A2000-XP, version 4.0, Aspect Medical Systems, Newton, USA). Monitoring quality was assessed by a correlation between RASS and BIS values. These values were assessed by single regression analysis and a P value of <0.05 was considered significant. There was a significant correlation between RASS and BIS values (P = 3 × 10(-12), R (2) = 0.67) in the remifentanil group, but not in the control group (P = 0.50, R (2) = 0.057). The administration of low-dose remifentanil makes BIS a more precise tool for sedated patients under mechanical ventilation in the ICU. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Japan | 1 | 3% |
Canada | 1 | 3% |
Unknown | 30 | 94% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 8 | 25% |
Other | 5 | 16% |
Student > Ph. D. Student | 3 | 9% |
Student > Master | 3 | 9% |
Student > Bachelor | 2 | 6% |
Other | 8 | 25% |
Unknown | 3 | 9% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 18 | 56% |
Nursing and Health Professions | 3 | 9% |
Agricultural and Biological Sciences | 2 | 6% |
Pharmacology, Toxicology and Pharmaceutical Science | 2 | 6% |
Engineering | 2 | 6% |
Other | 1 | 3% |
Unknown | 4 | 13% |