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Gene profiling of Chikungunya virus arthritis in a mouse model reveals significant overlap with rheumatoid arthritis

Overview of attention for article published in Arthritis & Rheumatism, October 2012
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Title
Gene profiling of Chikungunya virus arthritis in a mouse model reveals significant overlap with rheumatoid arthritis
Published in
Arthritis & Rheumatism, October 2012
DOI 10.1002/art.34631
Pubmed ID
Authors

Helder I. Nakaya, Joy Gardner, Yee‐Suan Poo, Lee Major, Bali Pulendran, Andreas Suhrbier

Abstract

Chikungunya virus (CHIKV) is a mosquito-borne alphavirus that causes a chronic debilitating polyarthralgia/polyarthritis, for which current treatments are often inadequate. To assess whether new drugs being developed for rheumatoid arthritis (RA) might find utility in the treatment of alphaviral arthritides, we sought to determine whether the inflammatory gene expression signature of CHIKV arthritis shows any similarities with RA or collagen-induced arthritis (CIA), a mouse model of RA.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 139 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 3 2%
Colombia 1 <1%
Brazil 1 <1%
Saint Kitts and Nevis 1 <1%
United Kingdom 1 <1%
South Africa 1 <1%
Unknown 131 94%

Demographic breakdown

Readers by professional status Count As %
Researcher 28 20%
Student > Ph. D. Student 20 14%
Student > Master 17 12%
Student > Bachelor 15 11%
Other 10 7%
Other 28 20%
Unknown 21 15%
Readers by discipline Count As %
Agricultural and Biological Sciences 34 24%
Medicine and Dentistry 29 21%
Immunology and Microbiology 24 17%
Biochemistry, Genetics and Molecular Biology 7 5%
Nursing and Health Professions 3 2%
Other 15 11%
Unknown 27 19%