Title |
Xenotropic and polytropic murine leukemia virus-related sequences are not detected in the majority of patients with chronic fatigue syndrome.
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Published in |
new microbiologica, June 2012
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Pubmed ID | |
Authors |
Stefania Paolucci, Antonio Piralla, Cinzia Zanello, Lorenzo Minoli, Fausto Baldanti |
Abstract |
XMRV and polytropic MLV-related virus have been controversially associated with chronic fatigue syndrome (CFS). Subsequent reports failed to detect XMRV and MLV-related virus in CFS patients, and the previous results have been interpreted as a massive laboratory contamination by mouse DNA sequences. Among 12 sequential CFS patients, two were positive for XMRV/MLV sequences. In contrast, 40 selected control subjects were negative. CSF patients and controls were negative for mitochondrial mouse-specific DNA sequences. These findings do not confirm the high frequency of MLV-related viruses infection in CFS patients, but also contrast the widespread laboratory contamination previously suggested. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United Kingdom | 1 | 20% |
United States | 1 | 20% |
Unknown | 3 | 60% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 4 | 80% |
Practitioners (doctors, other healthcare professionals) | 1 | 20% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 17 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Other | 4 | 24% |
Student > Ph. D. Student | 3 | 18% |
Student > Doctoral Student | 3 | 18% |
Researcher | 2 | 12% |
Lecturer > Senior Lecturer | 1 | 6% |
Other | 1 | 6% |
Unknown | 3 | 18% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 4 | 24% |
Agricultural and Biological Sciences | 3 | 18% |
Nursing and Health Professions | 2 | 12% |
Business, Management and Accounting | 1 | 6% |
Arts and Humanities | 1 | 6% |
Other | 2 | 12% |
Unknown | 4 | 24% |