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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Liquid biopsy-based clinical research in early breast cancer: The EORTC 90091-10093 Treat CTC trial
|
|---|---|
| Published in |
European Journal of Cancer (1965), June 2016
|
| DOI | 10.1016/j.ejca.2016.04.024 |
| Pubmed ID | |
| Authors |
Michail Ignatiadis, Brigitte Rack, Francoise Rothé, Sabine Riethdorf, Charles Decraene, Hervé Bonnefoi, Christian Dittrich, Carlo Messina, Melanie Beauvois, Elisabeth Trapp, Theodora Goulioti, Konstantinos Tryfonidis, Klaus Pantel, Madeline Repollet, Wolfgang Janni, Martine Piccart, Christos Sotiriou, Saskia Litiere, Jean-Yves Pierga |
| Abstract |
There is increasing evidence that breast cancer evolves over time under the selection pressure of systemic treatment. Today, treatment decisions in early breast cancer are based on primary tumour characteristics without considering the disease evolution. Chemoresistant micrometastatic disease is poorly characterised and thus it is not used in current clinical practice as a tool to personalise treatment approaches. The detection of chemoresistant circulating tumour cells (CTCs) has been shown to be associated with worse prognosis in early breast cancer. The ongoing Treat CTC trial is the first international, liquid biopsy-based trial evaluating the concept of targeting chemoresistant minimal residual disease: detection of CTCs following adjuvant chemotherapy (adjuvant cohort) or neoadjuvant chemotherapy in patients who did not achieve pathological complete response (neoadjuvant cohort). This article presents the rational and design of this trial and the results of the pilot phase after 350 patients have been screened and provides insights that might provide information for future trials using the liquid biopsy approach as a tool towards precision medicine (NCT01548677). |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 2 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 97 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Israel | 1 | 1% |
| Switzerland | 1 | 1% |
| Unknown | 95 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 14 | 14% |
| Student > Master | 13 | 13% |
| Student > Ph. D. Student | 12 | 12% |
| Student > Bachelor | 11 | 11% |
| Other | 10 | 10% |
| Other | 19 | 20% |
| Unknown | 18 | 19% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 30 | 31% |
| Biochemistry, Genetics and Molecular Biology | 18 | 19% |
| Agricultural and Biological Sciences | 10 | 10% |
| Computer Science | 2 | 2% |
| Pharmacology, Toxicology and Pharmaceutical Science | 2 | 2% |
| Other | 9 | 9% |
| Unknown | 26 | 27% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 22 March 2017.
All research outputs
#20,014,336
of 25,461,852 outputs
Outputs from European Journal of Cancer (1965)
#5,841
of 6,879 outputs
Outputs of similar age
#260,668
of 360,310 outputs
Outputs of similar age from European Journal of Cancer (1965)
#62
of 84 outputs
Altmetric has tracked 25,461,852 research outputs across all sources so far. This one is in the 18th percentile – i.e., 18% of other outputs scored the same or lower than it.
So far Altmetric has tracked 6,879 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.1. This one is in the 12th percentile – i.e., 12% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 360,310 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 23rd percentile – i.e., 23% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 84 others from the same source and published within six weeks on either side of this one. This one is in the 22nd percentile – i.e., 22% of its contemporaries scored the same or lower than it.