| Title |
Potential neuroprotective properties of epigallocatechin-3-gallate (EGCG)
|
|---|---|
| Published in |
Nutrition Journal, June 2016
|
| DOI | 10.1186/s12937-016-0179-4 |
| Pubmed ID | |
| Authors |
Neha Atulkumar Singh, Abul Kalam Azad Mandal, Zaved Ahmed Khan |
| Abstract |
Neurodegenerative diseases such as Alzheimer's disease (AD) and Parkinson's disease (PD) enforce an overwhelming social and economic burden on society. They are primarily characterized through the accumulation of modified proteins, which further trigger biological responses such as inflammation, oxidative stress, excitotoxicity and modulation of signalling pathways. In a hope for cure, these diseases have been studied extensively over the last decade to successfully develop symptom-oriented therapies. However, so far no definite cure has been found. Therefore, there is a need to identify a class of drug capable of reversing neural damage and preventing further neural death. This review therefore assesses the reliability of the neuroprotective benefits of epigallocatechin-gallate (EGCG) by shedding light on their biological, pharmacological, antioxidant and metal chelation properties, with emphasis on their ability to invoke a range of cellular mechanisms in the brain. It also discusses the possible use of nanotechnology to enhance the neuroprotective benefits of EGCG. |
X Demographics
The data shown below were collected from the profiles of 40 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Japan | 11 | 28% |
| United States | 2 | 5% |
| Netherlands | 1 | 3% |
| India | 1 | 3% |
| China | 1 | 3% |
| Canada | 1 | 3% |
| France | 1 | 3% |
| Unknown | 22 | 55% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 33 | 83% |
| Practitioners (doctors, other healthcare professionals) | 3 | 8% |
| Science communicators (journalists, bloggers, editors) | 2 | 5% |
| Scientists | 2 | 5% |
Mendeley readers
The data shown below were compiled from readership statistics for 298 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| India | 1 | <1% |
| Unknown | 297 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 41 | 14% |
| Student > Ph. D. Student | 37 | 12% |
| Student > Master | 36 | 12% |
| Researcher | 29 | 10% |
| Student > Doctoral Student | 17 | 6% |
| Other | 44 | 15% |
| Unknown | 94 | 32% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 37 | 12% |
| Agricultural and Biological Sciences | 28 | 9% |
| Neuroscience | 25 | 8% |
| Medicine and Dentistry | 23 | 8% |
| Pharmacology, Toxicology and Pharmaceutical Science | 22 | 7% |
| Other | 53 | 18% |
| Unknown | 110 | 37% |
Attention Score in Context
This research output has an Altmetric Attention Score of 50. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 January 2024.
All research outputs
#865,858
of 25,782,917 outputs
Outputs from Nutrition Journal
#251
of 1,529 outputs
Outputs of similar age
#16,183
of 356,985 outputs
Outputs of similar age from Nutrition Journal
#4
of 24 outputs
Altmetric has tracked 25,782,917 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 96th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,529 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 40.6. This one has done well, scoring higher than 83% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 356,985 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 95% of its contemporaries.
We're also able to compare this research output to 24 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 83% of its contemporaries.