Title |
Detection of P. aeruginosa harboring blaCTX-M-2, blaGES-1 and blaGES-5,blaIMP-1 and blaSPM-1causing infections in Brazilian tertiary-care hospital
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Published in |
BMC Infectious Diseases, August 2012
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DOI | 10.1186/1471-2334-12-176 |
Pubmed ID | |
Authors |
Milena Polotto, Tiago Casella, Maria Gabriela de Lucca Oliveira, Fernando G Rúbio, Mauricio L Nogueira, Margarete TG de Almeida, Mara CL Nogueira |
Abstract |
Nosocomial infections caused by Pseudomonas aeruginosa presenting resistance to beta-lactam drugs are one of the most challenging targets for antimicrobial therapy, leading to substantial increase in mortality rates in hospitals worldwide. In this context, P. aeruginosa harboring acquired mechanisms of resistance, such as production of metallo-beta-lactamase (MBLs) and extended-spectrum beta-lactamases (ESBLs) have the highest clinical impact. Hence, this study was designed to investigate the presence of genes codifying for MBLs and ESBLs among carbapenem resistant P. aeruginosa isolated in a Brazilian 720-bed teaching tertiary care hospital. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | <1% |
Nigeria | 1 | <1% |
Brazil | 1 | <1% |
Unknown | 104 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 25 | 23% |
Researcher | 17 | 16% |
Student > Bachelor | 13 | 12% |
Student > Ph. D. Student | 13 | 12% |
Student > Doctoral Student | 10 | 9% |
Other | 15 | 14% |
Unknown | 14 | 13% |
Readers by discipline | Count | As % |
---|---|---|
Biochemistry, Genetics and Molecular Biology | 22 | 21% |
Agricultural and Biological Sciences | 21 | 20% |
Immunology and Microbiology | 18 | 17% |
Medicine and Dentistry | 14 | 13% |
Pharmacology, Toxicology and Pharmaceutical Science | 5 | 5% |
Other | 11 | 10% |
Unknown | 16 | 15% |