| Title |
Significance of long-chain polyunsaturated fatty acids (PUFAs) for the development and behaviour of children
|
|---|---|
| Published in |
European Journal of Pediatrics, August 2009
|
| DOI | 10.1007/s00431-009-1035-8 |
| Pubmed ID | |
| Authors |
Jan Philipp Schuchardt, Michael Huss, Manuela Stauss-Grabo, Andreas Hahn |
| Abstract |
omega-6 and omega-3 polyunsaturated fatty acids (PUFAs) play a central role in the normal development and functioning of the brain and central nervous system. Long-chain PUFAs (LC-PUFAs) such as eicosapentaenoic acid (EPA, C20:5omega-3), docosahexaenoic acid (DHA, C22:6omega-3) and arachidonic acid (AA, C20:4omega-6), in particular, are involved in numerous neuronal processes, ranging from effects on membrane fluidity to gene expression regulation. Deficiencies and imbalances of these nutrients, not only during the developmental phase but throughout the whole life span, have significant effects on brain function. Numerous observational studies have shown a link between childhood developmental disorders and omega-6:omega-3 fatty acid imbalances. For instance, neurocognitive disorders such as attention-deficit hyperactivity disorder (ADHD), dyslexia, dyspraxia and autism spectrum disorders are often associated with a relative lack of omega-3 fatty acids. In addition to a high omega-6 fatty acid intake and, in many cases, an insufficient supply of omega-3 fatty acids among the population, evidence is increasing to suggest that PUFA metabolism can be impaired in individuals with ADHD. In this context, PUFA imbalances are being discussed as potential risk factors for neurodevelopmental disorders. Another focus is whether the nutritive PUFA requirements-especially long-chain omega-3 fatty acid requirements-are higher among some individuals. Meanwhile, several controlled studies investigated the clinical benefits of LC-PUFA supplementation in affected children and adolescents, with occasionally conflicting results. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Norway | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 336 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Australia | 3 | <1% |
| Brazil | 2 | <1% |
| Ireland | 1 | <1% |
| Portugal | 1 | <1% |
| India | 1 | <1% |
| United Kingdom | 1 | <1% |
| Spain | 1 | <1% |
| Japan | 1 | <1% |
| Unknown | 325 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 57 | 17% |
| Student > Master | 53 | 16% |
| Student > Ph. D. Student | 47 | 14% |
| Researcher | 33 | 10% |
| Other | 18 | 5% |
| Other | 53 | 16% |
| Unknown | 75 | 22% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 61 | 18% |
| Medicine and Dentistry | 59 | 18% |
| Psychology | 29 | 9% |
| Nursing and Health Professions | 26 | 8% |
| Biochemistry, Genetics and Molecular Biology | 17 | 5% |
| Other | 57 | 17% |
| Unknown | 87 | 26% |
Attention Score in Context
This research output has an Altmetric Attention Score of 17. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 March 2022.
All research outputs
#1,847,074
of 23,339,727 outputs
Outputs from European Journal of Pediatrics
#207
of 3,836 outputs
Outputs of similar age
#6,298
of 113,330 outputs
Outputs of similar age from European Journal of Pediatrics
#1
of 4 outputs
Altmetric has tracked 23,339,727 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 92nd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,836 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.8. This one has done particularly well, scoring higher than 94% of its peers.
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