| Title |
Genetics of Insulin Resistance and the Metabolic Syndrome
|
|---|---|
| Published in |
Current Cardiology Reports, June 2016
|
| DOI | 10.1007/s11886-016-0755-4 |
| Pubmed ID | |
| Authors |
Audrey E. Brown, Mark Walker |
| Abstract |
Insulin resistance and the metabolic syndrome are complex metabolic traits and key risk factors for the development of cardiovascular disease. They result from the interplay of environmental and genetic factors but the full extent of the genetic background to these conditions remains incomplete. Large-scale genome-wide association studies have helped advance the identification of common genetic variation associated with insulin resistance and the metabolic syndrome, and more recently, exome sequencing has allowed the identification of rare variants associated with the pathogenesis of these conditions. Many variants associated with insulin resistance are directly involved in glucose metabolism; however, functional studies are required to assess the contribution of other variants to the development of insulin resistance. Many genetic variants involved in the pathogenesis of the metabolic syndrome are associated with lipid metabolism. |
X Demographics
The data shown below were collected from the profiles of 5 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Canada | 1 | 20% |
| Cyprus | 1 | 20% |
| Unknown | 3 | 60% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 3 | 60% |
| Science communicators (journalists, bloggers, editors) | 1 | 20% |
| Practitioners (doctors, other healthcare professionals) | 1 | 20% |
Mendeley readers
The data shown below were compiled from readership statistics for 520 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Chile | 1 | <1% |
| Netherlands | 1 | <1% |
| Unknown | 518 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 90 | 17% |
| Student > Ph. D. Student | 66 | 13% |
| Student > Master | 51 | 10% |
| Researcher | 36 | 7% |
| Student > Doctoral Student | 20 | 4% |
| Other | 61 | 12% |
| Unknown | 196 | 38% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 86 | 17% |
| Biochemistry, Genetics and Molecular Biology | 82 | 16% |
| Agricultural and Biological Sciences | 30 | 6% |
| Nursing and Health Professions | 27 | 5% |
| Pharmacology, Toxicology and Pharmaceutical Science | 22 | 4% |
| Other | 52 | 10% |
| Unknown | 221 | 43% |
Attention Score in Context
This research output has an Altmetric Attention Score of 8. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 December 2023.
All research outputs
#4,654,983
of 24,991,957 outputs
Outputs from Current Cardiology Reports
#200
of 1,112 outputs
Outputs of similar age
#71,601
of 333,815 outputs
Outputs of similar age from Current Cardiology Reports
#4
of 14 outputs
Altmetric has tracked 24,991,957 research outputs across all sources so far. Compared to these this one has done well and is in the 81st percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,112 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.7. This one has done well, scoring higher than 81% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 333,815 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 78% of its contemporaries.
We're also able to compare this research output to 14 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 78% of its contemporaries.