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Peptidoglycan and muramyl dipeptide from Staphylococcus aureus induce the expression of VEGF-A in human limbal fibroblasts with the participation of TLR2-NFκB and NOD2-EGFR

Overview of attention for article published in Graefe's Archive for Clinical and Experimental Ophthalmology, August 2012
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Title
Peptidoglycan and muramyl dipeptide from Staphylococcus aureus induce the expression of VEGF-A in human limbal fibroblasts with the participation of TLR2-NFκB and NOD2-EGFR
Published in
Graefe's Archive for Clinical and Experimental Ophthalmology, August 2012
DOI 10.1007/s00417-012-2130-5
Pubmed ID
Authors

Marco Adán Juárez–Verdayes, Sandra Rodríguez–Martínez, Mario E. Cancino–Diaz, Juan C. Cancino–Diaz

Abstract

Keratitis caused by Staphylococcus aureus often leads to Vascular Endothelial Growth Factor (VEGF)-dependent neovascularization, but contribution of peptidoglycan (PGN), muramyl dipeptide (MDP) and lipoteichoic acid (LTA) from S. aureus to VEGF-dependent neovascularization has not been well-studied. This work was focused on the analysis of S. aureus cell wall components in the production of VEGF family members (VEGF-A, VEGF-B, VEGF-C and VEGF-D) in ocular limbal fibroblasts.

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Mendeley readers

The data shown below were compiled from readership statistics for 22 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 5%
United States 1 5%
Unknown 20 91%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 5 23%
Other 4 18%
Researcher 3 14%
Student > Doctoral Student 2 9%
Professor > Associate Professor 2 9%
Other 3 14%
Unknown 3 14%
Readers by discipline Count As %
Medicine and Dentistry 5 23%
Agricultural and Biological Sciences 4 18%
Immunology and Microbiology 4 18%
Biochemistry, Genetics and Molecular Biology 3 14%
Nursing and Health Professions 1 5%
Other 0 0%
Unknown 5 23%