| Title |
Interleukin-10 and Interleukin-10–Receptor Defects in Inflammatory Bowel Disease
|
|---|---|
| Published in |
Current Allergy and Asthma Reports, August 2012
|
| DOI | 10.1007/s11882-012-0286-z |
| Pubmed ID | |
| Authors |
Neil Shah, Jochen Kammermeier, Mamoun Elawad, Erik-Oliver Glocker |
| Abstract |
Inflammatory bowel disease (IBD) is a chronic inflammatory disease characterized by abdominal pain, bloody diarrhoea, and malabsorption leading to weight loss. It is considered the result of inadequate control of an excessive reaction of the immune system to the resident flora of the gut. Like other primary immunodeficiencies, IL-10 and IL-10 receptor (IL10R) deficiency present with IBD and demonstrate the sensitivity of the intestine to any changes of the immune system. Both IL-10 and IL10R deficiency cause severe early-onset enterocolitis and can be successfully treated by hematopoietic stem cell transplantation (HSCT). |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Australia | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Scientists | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 135 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Russia | 1 | <1% |
| Unknown | 134 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 28 | 21% |
| Student > Master | 23 | 17% |
| Student > Bachelor | 18 | 13% |
| Researcher | 17 | 13% |
| Other | 9 | 7% |
| Other | 17 | 13% |
| Unknown | 23 | 17% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 36 | 27% |
| Agricultural and Biological Sciences | 36 | 27% |
| Immunology and Microbiology | 13 | 10% |
| Biochemistry, Genetics and Molecular Biology | 9 | 7% |
| Nursing and Health Professions | 3 | 2% |
| Other | 9 | 7% |
| Unknown | 29 | 21% |
Attention Score in Context
This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 25 October 2022.
All research outputs
#7,230,420
of 23,575,346 outputs
Outputs from Current Allergy and Asthma Reports
#315
of 816 outputs
Outputs of similar age
#50,941
of 168,974 outputs
Outputs of similar age from Current Allergy and Asthma Reports
#11
of 23 outputs
Altmetric has tracked 23,575,346 research outputs across all sources so far. This one has received more attention than most of these and is in the 68th percentile.
So far Altmetric has tracked 816 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.1. This one has gotten more attention than average, scoring higher than 59% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 168,974 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 68% of its contemporaries.
We're also able to compare this research output to 23 others from the same source and published within six weeks on either side of this one. This one is in the 47th percentile – i.e., 47% of its contemporaries scored the same or lower than it.