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Mendeley readers
Attention Score in Context
| Title |
Augmented Renal Clearance in Traumatic Brain Injury: A Single-Center Observational Study of Atrial Natriuretic Peptide, Cardiac Output, and Creatinine Clearance
|
|---|---|
| Published in |
Journal of Neurotrauma, August 2016
|
| DOI | 10.1089/neu.2015.4328 |
| Pubmed ID | |
| Authors |
Andrew A. Udy, Paul Jarrett, Melissa Lassig-Smith, Janine Stuart, Therese Starr, Rachel Dunlop, Renae Deans, Jason A. Roberts, Siva Senthuran, Robert Boots, Kavita Bisht, Andrew C. Bulmer, Jeffrey Lipman |
| Abstract |
Augmented renal clearance (ARC) is being increasingly described in neurocritical care practice. The mechanisms driving this phenomenon are largely unknown. The aim of this project was therefore to explore changes in renal function, cardiac output (CO), and atrial natriuretic peptide (ANP) concentrations in patients with isolated traumatic brain injury (TBI). This prospective observational cohort study was conducted in a tertiary level university affiliated ICU. Patients with normal plasma creatinine concentrations (< 120 μmol/L) at admission and no history of chronic kidney disease, admitted with isolated TBI, were eligible for enrolment. Continuous CO measures were obtained using arterial pulse waveform analysis. 8-h urinary creatinine clearances (CLCR) were used to quantify renal function. ANP concentrations in plasma were measured on alternate days. Data were collected from study enrolment until ICU discharge, death, or day 15, which ever came first. Eleven patients, contributing 100 ICU-days of physiological data were enrolled into the study. Most participants were young men, requiring mechanical ventilation. The median ICU length of stay was 9.6 [7.8-13.0] days. Elevated CLCR measures (> 150mL/min) were frequent, and appeared to parallel changes in CO. Plasma ANP concentrations were also significantly elevated over the study period (minimum value = 243 pg/mL). These data suggest that ARC is likely to complicate the care of TBI patients with normal plasma creatinine concentrations, and may be driven by associated cardiovascular changes, and/or elevated plasma ANP concentrations. However, significant additional research is required to further understand these findings. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 59 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 59 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Other | 10 | 17% |
| Student > Master | 8 | 14% |
| Student > Bachelor | 6 | 10% |
| Student > Doctoral Student | 6 | 10% |
| Researcher | 6 | 10% |
| Other | 7 | 12% |
| Unknown | 16 | 27% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 20 | 34% |
| Pharmacology, Toxicology and Pharmaceutical Science | 13 | 22% |
| Neuroscience | 2 | 3% |
| Psychology | 2 | 3% |
| Nursing and Health Professions | 1 | 2% |
| Other | 0 | 0% |
| Unknown | 21 | 36% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 22 June 2016.
All research outputs
#20,657,128
of 25,377,790 outputs
Outputs from Journal of Neurotrauma
#2,348
of 2,767 outputs
Outputs of similar age
#263,143
of 337,652 outputs
Outputs of similar age from Journal of Neurotrauma
#31
of 33 outputs
Altmetric has tracked 25,377,790 research outputs across all sources so far. This one is in the 10th percentile – i.e., 10% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,767 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.2. This one is in the 7th percentile – i.e., 7% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 337,652 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 11th percentile – i.e., 11% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 33 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.