| Title |
Potential Impact of Benzodiazepine Use on the Rate of Hip Fractures in Five Large European Countries and the United States
|
|---|---|
| Published in |
Calcified Tissue International, May 2012
|
| DOI | 10.1007/s00223-012-9603-8 |
| Pubmed ID | |
| Authors |
T. P. Khong, F. de Vries, J. S. B. Goldenberg, O. H. Klungel, N. J. Robinson, Luisa Ibáñez, H. Petri |
| Abstract |
Benzodiazepine use increases the risk of falls and has been associated with an increased risk of hip fractures. Our aim was to estimate the possible population impact of the use of benzodiazepines on the rate of hip fracture in France, Germany, Italy, Spain, the United Kingdom, and the United States. We conducted a literature review to estimate the pooled relative risk (RR) for hip fractures and use of benzodiazepines. Prevalence rates of benzodiazepine use in 2009 were calculated for each country using the IMS MIDAS database and three public databases in Denmark, the Netherlands, and Norway. Both the RR and prevalence rates were used for calculation of population attributable risks (PARs) of hip fractures associated with benzodiazepine use. The literature review showed an increased risk of hip fractures in benzodiazepine users (RR = 1.4, 95 % CI 1.2-1.6). Rate of benzodiazepine use showed considerable differences between countries, ranging from 4.7 % to 22.3 % of population ever in a 1-year period. These are reflected in results for the PARs; estimated attributions of benzodiazepines to the rate of hip fractures were 1.8 %, 95 % CI 1.1-2.6 (Germany); 2.0 %, 95 % CI 1.2-2.8 (United Kingdom); 5.2 %, 95 % CI 3.2-7.3 (Italy); 7.4 %, 95 % CI 4.5-10.0 (France); 8.0 %, 95 % CI 4.9-11.0 (United States); and 8.2 %, 95 % CI 5.1-12.0 (Spain). PAR estimates suggest that the potential attribution of benzodiazepine use on the population rate of hip fractures in the five specified European countries and the United States varies between 1.8 % and 8.2 %. During the next phase of the IMI-PROTECT study, a comparison with individual patient data will show whether this approach is valid. |
X Demographics
The data shown below were collected from the profiles of 37 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Spain | 19 | 51% |
| Colombia | 1 | 3% |
| Japan | 1 | 3% |
| France | 1 | 3% |
| Unknown | 15 | 41% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 29 | 78% |
| Practitioners (doctors, other healthcare professionals) | 6 | 16% |
| Science communicators (journalists, bloggers, editors) | 1 | 3% |
| Scientists | 1 | 3% |
Mendeley readers
The data shown below were compiled from readership statistics for 94 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| France | 1 | 1% |
| Unknown | 93 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 17 | 18% |
| Student > Ph. D. Student | 13 | 14% |
| Student > Bachelor | 11 | 12% |
| Student > Doctoral Student | 8 | 9% |
| Student > Master | 8 | 9% |
| Other | 16 | 17% |
| Unknown | 21 | 22% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 41 | 44% |
| Pharmacology, Toxicology and Pharmaceutical Science | 9 | 10% |
| Nursing and Health Professions | 6 | 6% |
| Psychology | 3 | 3% |
| Agricultural and Biological Sciences | 3 | 3% |
| Other | 10 | 11% |
| Unknown | 22 | 23% |
Attention Score in Context
This research output has an Altmetric Attention Score of 32. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 July 2020.
All research outputs
#1,259,861
of 25,602,335 outputs
Outputs from Calcified Tissue International
#46
of 1,890 outputs
Outputs of similar age
#6,631
of 176,425 outputs
Outputs of similar age from Calcified Tissue International
#3
of 16 outputs
Altmetric has tracked 25,602,335 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 95th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,890 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.2. This one has done particularly well, scoring higher than 97% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 176,425 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 96% of its contemporaries.
We're also able to compare this research output to 16 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 87% of its contemporaries.