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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Post-translational regulation of inflammasomes
|
|---|---|
| Published in |
Cellular & Molecular Immunology, June 2016
|
| DOI | 10.1038/cmi.2016.29 |
| Pubmed ID | |
| Authors |
Jie Yang, Zhonghua Liu, Tsan Sam Xiao |
| Abstract |
Inflammasomes play essential roles in immune protection against microbial infections. However, excessive inflammation is implicated in various human diseases, including autoinflammatory syndromes, diabetes, multiple sclerosis, cardiovascular disorders and neurodegenerative diseases. Therefore, precise regulation of inflammasome activities is critical for adequate immune protection while limiting collateral tissue damage. In this review, we focus on the emerging roles of post-translational modifications (PTMs) that regulate activation of the NLRP3, NLRP1, NLRC4, AIM2 and IFI16 inflammasomes. We anticipate that these types of PTMs will be identified in other types of and less well-characterized inflammasomes. Because these highly diverse and versatile PTMs shape distinct inflammatory responses in response to infections and tissue damage, targeting the enzymes involved in these PTMs will undoubtedly offer opportunities for precise modulation of inflammasome activities under various pathophysiological conditions.Cellular & Molecular Immunology advance online publication, 27 June 2016; doi:10.1038/cmi.2016.29. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 2 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 195 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 1% |
| Brazil | 1 | <1% |
| Unknown | 192 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 43 | 22% |
| Researcher | 27 | 14% |
| Student > Bachelor | 20 | 10% |
| Student > Master | 19 | 10% |
| Student > Doctoral Student | 13 | 7% |
| Other | 29 | 15% |
| Unknown | 44 | 23% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 37 | 19% |
| Agricultural and Biological Sciences | 37 | 19% |
| Immunology and Microbiology | 27 | 14% |
| Medicine and Dentistry | 19 | 10% |
| Neuroscience | 11 | 6% |
| Other | 18 | 9% |
| Unknown | 46 | 24% |
Attention Score in Context
This research output has an Altmetric Attention Score of 14. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 30 June 2021.
All research outputs
#2,221,044
of 22,879,161 outputs
Outputs from Cellular & Molecular Immunology
#163
of 1,284 outputs
Outputs of similar age
#42,168
of 352,119 outputs
Outputs of similar age from Cellular & Molecular Immunology
#2
of 14 outputs
Altmetric has tracked 22,879,161 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 90th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,284 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 18.3. This one has done well, scoring higher than 87% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 352,119 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 87% of its contemporaries.
We're also able to compare this research output to 14 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 85% of its contemporaries.