| Title |
Barriers to and facilitative processes of endocrine therapy adherence among women with breast cancer
|
|---|---|
| Published in |
Breast Cancer Research and Treatment, June 2016
|
| DOI | 10.1007/s10549-016-3871-3 |
| Pubmed ID | |
| Authors |
Emma E. Bright, Keith J. Petrie, Ann H. Partridge, Annette L. Stanton |
| Abstract |
The treatment of chronic illness, and the prevention of disease progression and recurrence, often involve long-term adherence to prescription medications in breast cancer. Despite the survival benefit of endocrine therapies, nonadherence remains high. In this study, we examined barriers to and facilitators of endocrine therapy adherence among women with breast cancer (n = 1371). Participants currently taking tamoxifen or aromatase inhibitors were recruited from Dr. Susan Love Research Foundation's Army of Women(®) Registry. Participants responded online to open-ended and close-ended questions about thoughts, feelings, and behaviors relevant to endocrine therapy. Two weeks later, women were invited to complete a second online questionnaire regarding current endocrine therapy adherence. Approximately one-third (36 %) of participants reported the presence of factors that make endocrine therapy difficult; reporting any barrier to medication adherence was significantly associated with nonadherence (P < 0.001). In addition, 31 % of women used one or more strategies to maintain their motivation to adhere and the use of cognitive self-talk (e.g., thoughts regarding endocrine therapy efficacy) was related to higher adherence. Hierarchical linear regressions revealed a significant behavioral barrier × behavioral facilitator interaction (P < 0.05); participants who endorsed a behavioral barrier in the absence of a behavioral facilitator reported the lowest adherence. Findings suggest that a sizeable minority of women face barriers to taking endocrine therapy, which are associated with nonadherence. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 78 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 1% |
| Unknown | 77 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 11 | 14% |
| Student > Bachelor | 11 | 14% |
| Researcher | 10 | 13% |
| Student > Doctoral Student | 7 | 9% |
| Student > Master | 7 | 9% |
| Other | 7 | 9% |
| Unknown | 25 | 32% |
| Readers by discipline | Count | As % |
|---|---|---|
| Psychology | 18 | 23% |
| Medicine and Dentistry | 12 | 15% |
| Pharmacology, Toxicology and Pharmaceutical Science | 9 | 12% |
| Nursing and Health Professions | 8 | 10% |
| Business, Management and Accounting | 2 | 3% |
| Other | 5 | 6% |
| Unknown | 24 | 31% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 June 2016.
All research outputs
#20,334,427
of 22,879,161 outputs
Outputs from Breast Cancer Research and Treatment
#4,110
of 4,659 outputs
Outputs of similar age
#305,328
of 352,727 outputs
Outputs of similar age from Breast Cancer Research and Treatment
#75
of 100 outputs
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