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The Economic Burden of Hospital-Acquired Clostridium difficile Infection: A Population-Based Matched Cohort Study

Overview of attention for article published in Infection control and hospital epidemiology (Online), June 2016
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (82nd percentile)
  • Good Attention Score compared to outputs of the same age and source (77th percentile)

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15 X users
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1 Facebook page

Citations

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20 Dimensions

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71 Mendeley
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Title
The Economic Burden of Hospital-Acquired Clostridium difficile Infection: A Population-Based Matched Cohort Study
Published in
Infection control and hospital epidemiology (Online), June 2016
DOI 10.1017/ice.2016.122
Pubmed ID
Authors

Natasha Nanwa, Jeffrey C. Kwong, Murray Krahn, Nick Daneman, Hong Lu, Peter C. Austin, Anand Govindarajan, Laura C. Rosella, Suzanne M. Cadarette, Beate Sander

Abstract

BACKGROUND High-quality cost estimates for hospital-acquired Clostridium difficile infection (CDI) are vital evidence for healthcare policy and decision-making. OBJECTIVE To evaluate the costs attributable to hospital-acquired CDI from the healthcare payer perspective. METHODS We conducted a population-based propensity-score matched cohort study of incident hospitalized subjects diagnosed with CDI (those with the International Statistical Classification of Diseases and Related Health Problems, 10th Revision, Canada code A04.7) from January 1, 2003, through December 31, 2010, in Ontario, Canada. Infected subjects were matched to uninfected subjects (those without the code A04.7) on age, sex, comorbidities, geography, and other variables, and followed up through December 31, 2011. We stratified results by elective and nonelective admissions. The main study outcomes were up-to-3-year costs, which were evaluated in 2014 Canadian dollars. RESULTS We identified 28,308 infected subjects (mean annual incidence, 27.9 per 100,000 population, 3.3 per 1,000 admissions), with a mean age of 71.5 years (range, 0-107 years), 54.0% female, and 8.0% elective admissions. For elective admission subjects, cumulative mean attributable 1-, 2-, and 3-year costs adjusted for survival (undiscounted) were $32,151 (95% CI, $28,192-$36,005), $34,843 ($29,298-$40,027), and $37,171 ($30,364-$43,415), respectively. For nonelective admission subjects, the corresponding costs were $21,909 ($21,221-$22,609), $26,074 ($25,180-$27,014), and $29,944 ($28,873-$31,086), respectively. CONCLUSIONS Hospital-acquired CDI is associated with substantial healthcare costs. To the best of our knowledge, this study is the first CDI costing study to present longitudinal costs. New strategies may be warranted to mitigate this costly infectious disease. Infect Control Hosp Epidemiol 2016;1-11.

X Demographics

X Demographics

The data shown below were collected from the profiles of 15 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 71 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Spain 1 1%
United States 1 1%
Canada 1 1%
Unknown 68 96%

Demographic breakdown

Readers by professional status Count As %
Researcher 16 23%
Student > Ph. D. Student 11 15%
Student > Master 7 10%
Student > Doctoral Student 4 6%
Professor 4 6%
Other 12 17%
Unknown 17 24%
Readers by discipline Count As %
Medicine and Dentistry 22 31%
Nursing and Health Professions 3 4%
Immunology and Microbiology 3 4%
Biochemistry, Genetics and Molecular Biology 2 3%
Economics, Econometrics and Finance 2 3%
Other 13 18%
Unknown 26 37%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 10. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 April 2018.
All research outputs
#3,789,098
of 25,373,627 outputs
Outputs from Infection control and hospital epidemiology (Online)
#1,208
of 5,014 outputs
Outputs of similar age
#66,390
of 369,933 outputs
Outputs of similar age from Infection control and hospital epidemiology (Online)
#105
of 468 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. Compared to these this one has done well and is in the 85th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 5,014 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 14.5. This one has done well, scoring higher than 75% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 369,933 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 82% of its contemporaries.
We're also able to compare this research output to 468 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 77% of its contemporaries.