Title |
MethPed: an R package for the identification of pediatric brain tumor subtypes
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Published in |
BMC Bioinformatics, July 2016
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DOI | 10.1186/s12859-016-1144-0 |
Pubmed ID | |
Authors |
Mohammad Tanvir Ahamed, Anna Danielsson, Szilárd Nemes, Helena Carén |
Abstract |
DNA methylation profiling of pediatric brain tumors offers a new way of diagnosing and subgrouping these tumors which improves current clinical diagnostics based on histopathology. We have therefore developed the MethPed classifier, which is a multiclass random forest algorithm, based on DNA methylation profiles from many subgroups of pediatric brain tumors. We developed an R package that implements the MethPed classifier, making it easily available and accessible. The package can be used for estimating the probability that an unknown sample belongs to each of nine pediatric brain tumor diagnoses/subgroups. The MethPed R package efficiently classifies pediatric brain tumors using the developed MethPed classifier. MethPed is available via Bioconductor: http://bioconductor.org/packages/MethPed/. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United States | 2 | 22% |
Portugal | 1 | 11% |
Belgium | 1 | 11% |
Unknown | 5 | 56% |
Demographic breakdown
Type | Count | As % |
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Scientists | 4 | 44% |
Members of the public | 4 | 44% |
Practitioners (doctors, other healthcare professionals) | 1 | 11% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 19 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Bachelor | 4 | 21% |
Researcher | 4 | 21% |
Student > Ph. D. Student | 3 | 16% |
Student > Master | 2 | 11% |
Student > Doctoral Student | 1 | 5% |
Other | 2 | 11% |
Unknown | 3 | 16% |
Readers by discipline | Count | As % |
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Biochemistry, Genetics and Molecular Biology | 3 | 16% |
Medicine and Dentistry | 3 | 16% |
Agricultural and Biological Sciences | 2 | 11% |
Engineering | 2 | 11% |
Computer Science | 2 | 11% |
Other | 3 | 16% |
Unknown | 4 | 21% |