| Title |
Epigenetic control on cell fate choice in neural stem cells
|
|---|---|
| Published in |
Protein & Cell, May 2012
|
| DOI | 10.1007/s13238-012-2916-6 |
| Pubmed ID | |
| Authors |
Xiao-Ling Hu, Yuping Wang, Qin Shen |
| Abstract |
Derived from neural stem cells (NSCs) and progenitor cells originated from the neuroectoderm, the nervous system presents an unprecedented degree of cellular diversity, interwoven to ensure correct connections for propagating information and responding to environmental cues. NSCs and progenitor cells must integrate cell-intrinsic programs and environmental cues to achieve production of appropriate types of neurons and glia at appropriate times and places during development. These developmental dynamics are reflected in changes in gene expression, which is regulated by transcription factors and at the epigenetic level. From early commitment of neural lineage to functional plasticity in terminal differentiated neurons, epigenetic regulation is involved in every step of neural development. Here we focus on the recent advance in our understanding of epigenetic regulation on orderly generation of diverse neural cell types in the mammalian nervous system, an important aspect of neural development and regenerative medicine. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Scientists | 1 | 50% |
| Members of the public | 1 | 50% |
Mendeley readers
The data shown below were compiled from readership statistics for 91 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 1% |
| Mexico | 1 | 1% |
| Spain | 1 | 1% |
| United States | 1 | 1% |
| Poland | 1 | 1% |
| Unknown | 86 | 95% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 27 | 30% |
| Researcher | 13 | 14% |
| Student > Master | 12 | 13% |
| Student > Bachelor | 12 | 13% |
| Student > Postgraduate | 6 | 7% |
| Other | 13 | 14% |
| Unknown | 8 | 9% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 41 | 45% |
| Biochemistry, Genetics and Molecular Biology | 13 | 14% |
| Neuroscience | 8 | 9% |
| Medicine and Dentistry | 8 | 9% |
| Psychology | 3 | 3% |
| Other | 8 | 9% |
| Unknown | 10 | 11% |
Attention Score in Context
This research output has an Altmetric Attention Score of 5. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 December 2020.
All research outputs
#6,198,581
of 22,675,759 outputs
Outputs from Protein & Cell
#229
of 737 outputs
Outputs of similar age
#43,168
of 163,476 outputs
Outputs of similar age from Protein & Cell
#1
of 14 outputs
Altmetric has tracked 22,675,759 research outputs across all sources so far. This one has received more attention than most of these and is in the 72nd percentile.
So far Altmetric has tracked 737 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 12.4. This one has gotten more attention than average, scoring higher than 68% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 163,476 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 73% of its contemporaries.
We're also able to compare this research output to 14 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 92% of its contemporaries.